{"title":"卵巢生殖细胞肿瘤与博莱霉素致肺损伤","authors":"P. Barnardt, S. Griffith-Richards","doi":"10.1080/20742835.2018.1479213","DOIUrl":null,"url":null,"abstract":"Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly affect young people. The potential side effects and long-term toxicities should be considered. The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin-associated pulmonary toxicity.","PeriodicalId":41638,"journal":{"name":"Southern African Journal of Gynaecological Oncology","volume":"10 1","pages":"30 - 33"},"PeriodicalIF":0.1000,"publicationDate":"2018-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20742835.2018.1479213","citationCount":"0","resultStr":"{\"title\":\"Ovarian germ cell tumour and bleomycin-induced lung injury\",\"authors\":\"P. Barnardt, S. Griffith-Richards\",\"doi\":\"10.1080/20742835.2018.1479213\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly affect young people. The potential side effects and long-term toxicities should be considered. The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin-associated pulmonary toxicity.\",\"PeriodicalId\":41638,\"journal\":{\"name\":\"Southern African Journal of Gynaecological Oncology\",\"volume\":\"10 1\",\"pages\":\"30 - 33\"},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2018-07-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/20742835.2018.1479213\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Southern African Journal of Gynaecological Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/20742835.2018.1479213\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Southern African Journal of Gynaecological Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/20742835.2018.1479213","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Ovarian germ cell tumour and bleomycin-induced lung injury
Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly affect young people. The potential side effects and long-term toxicities should be considered. The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin-associated pulmonary toxicity.