卵巢生殖细胞肿瘤与博莱霉素致肺损伤

IF 0.1 Q4 OBSTETRICS & GYNECOLOGY
P. Barnardt, S. Griffith-Richards
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引用次数: 0

摘要

博莱霉素是一种具有抗肿瘤活性的抗生素,是治疗许多肿瘤恶性肿瘤如淋巴瘤和生殖细胞肿瘤的重要药物。这些肿瘤是可以治愈的,主要影响年轻人。应考虑潜在的副作用和长期毒性。博莱霉素治疗的主要限制是肺毒性,约10%的病例可能危及生命。本文报告一例卵巢混合生殖细胞瘤,其表现为博莱霉素相关的肺毒性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Ovarian germ cell tumour and bleomycin-induced lung injury
Bleomycin, an antibiotic agent with antitumour activity, is an important drug in the management of many oncological malignancies such as lymphoma and germ cell tumours. These tumours are potentially curable and mostly affect young people. The potential side effects and long-term toxicities should be considered. The major limitation of bleomycin therapy is pulmonary toxicity and may be life threatening in about 10% of cases. This article reports a case of an ovarian mixed germ cell tumour, which presented with bleomycin-associated pulmonary toxicity.
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