大豆甜菜对高血糖动物模型褐家鼠的抗糖尿病作用

I. P. D. Arjita, D. J. Sukmana, H. Hardani, Diani Sri Hidayati, I. P. B. A. Saputra
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引用次数: 0

摘要

糖尿病(DM)的治疗通常是通过优化均衡饮食。大豆和红薯含有很好的抗氧化剂,可以作为糖尿病患者的健康食品。大豆和红薯被加工成大豆酸奶。本研究旨在通过链脲佐菌素检测大豆酸奶对实验动物褐家鼠高血糖诱导的降糖作用。本研究采用实验设计,共40只实验动物。这项研究于2022年在马塔兰的Medica Farma Husada理工实验室进行。用链脲佐菌素(STZ)诱导的实验动物分别口服3 ml和3.5 ml的大豆酸奶。实验动物每周用血糖仪测定空腹血糖(FBG)水平,每3天测定体重(BW)。所得结果用方差分析检验进行统计分析。试验结果显示,两组患者血糖水平差异有统计学意义(p0,05)。由此可见,饲喂大豆可影响试验动物的空腹血糖水平,但不影响试验动物的体重。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Soy-Ipoghurt as an antidiabetic on hiperglicemic animal modelling Rattus norvegicus
Treatment of Diabetes Mellitus (DM) is generally through optimizing a balanced diet. Soybeans and sweet potatoes have good antioxidants and can be developed as healthy foods for people with diabetes. Soybeans and sweet potatoes are processed into Soy-yoghurt. This study aims to determine the potential of soy yogurt as an antidiabetic in experimental animals, Rattus norvegicus induced by hyperglycemia, using Streptozotocin. This study used a experiment design with a total of 40 experimental animals. The research was conducted at the Medica Farma Husada Polytechnic Laboratory, Mataram, in 2022. The experimental animals that Streptozotocin (STZ) induced were then given Soy-yogurt orally at 3 ml and 3.5 ml doses. Experimental animals' Fasting Blood Glucose (FBG) levels were measured weekly using a Glucometer, while body weight (BW) was measured every three days. The results obtained were then analyzed statistically using the ANOVA test. The test results showed that there was a significant difference in blood sugar levels (p<0,05) in fasting given soy but no difference in BW (p>0,05). This study concludes that the provision of soybeans can affect the level of FBG  of the experimental animals but does not affect the BW of the experimental animals.
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