与COVID-19相关的细菌感染以及使用许多常见抗生素治疗这些感染的效果

Q4 Medicine
Dhuha Mahdi Jabir
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引用次数: 3

摘要

背景与目的:COVID-19患者未被发现的合并感染可能会产生严重的临床后果,包括住院率和死亡率增加。目前的研究是对从2021年2月到2021年3月在伊拉克迪瓦尼耶隔离的455名确诊为新型冠状病毒病的患者进行的。该研究的目的是调查与该病毒相关的继发性细菌感染以及使用一些常用抗生素(如阿奇霉素、β -内酰胺、环丙沙星和头孢曲松)的效果。材料与方法:对所有确诊感染后7天(Real-Time PCR)检测为COVID-19阳性的患者采集痰液样本。将样品在一组培养基上划线,然后转移到纯培养物中进行诊断,并使用Vitek -2紧凑系统技术测定其对抗生素的敏感性。结果:结果显示,耐甲氧西林和敏感金黄色葡萄球菌是最常见的分离种,占85%,其次是铜绿假单胞菌,占78%,其次是肺炎链球菌,占60%,鲍曼不动杆菌占64%,嗜肺军团菌占60%。此外,还观察到许多真菌。大多数分离菌株对研究中使用的抗生素具有耐药性。结论:本研究认为这些抗生素对感染无治疗作用。尽管如此,它可能会导致新的耐多药耐多药物种的出现,导致死亡率增加。此外,过度使用抗生素可能导致死亡率增加。《伊朗医学微生物学杂志》版权归伊朗微生物学会所有,未经版权所有者明确书面许可,其内容不得复制或通过电子邮件发送到多个网站或发布到listserv。但是,用户可以打印、下载或通过电子邮件发送文章供个人使用。这可以删节。对副本的准确性不作任何保证。用户应参阅原始出版版本的材料的完整。(版权适用于所有人。)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bacterial Infections associated with COVID-19 and the effect of using many common antibiotics in the treatment these infections
Background and Aim: Undetected coinfections in COVID-19 patients may have serious clinical consequences, including increased hospitalization and mortality. The current study was conducted on 455 patients diagnosed with the new epidemic coronavirus disease who were admitted to quarantine halls in Diwaniyah in Iraq for one month, from February 2021 to March 2021. The aim of the study was to investigate secondary bacterial infections associated with the virus and the effect of using some commonly used antibiotics such as azithromycin, Beta-lactam, ciprofloxacin, and ceftriaxone. Materials and Methods: Sputum samples were collected from all patients who tested positive for COVID-19 (Real-Time PCR) seven days after confirming the infection with the virus. The samples were streaked on a group of culture media, then transferred to pure cultures and diagnosed, and their sensitivity to antibiotics was determined using the Vitek -2 compact system technique. Results: According to the findings, the two strains of methicillin-resistant and Staphylococcus aureus sensitive were the most common isolated species with a percentage of 85%, followed by Pseudomonas aeruginosa 78%, in addition to Streptococcus pneumonia 60%, Acinetobacter baumannii 64%, and Legionella pneumophila 60%. Also, many fungi were observed. Most isolated strains were resistant to antibiotics used in the study. Conclusion: The study concluded that these antibiotics have no role in treating the infection. Still, it may contribute to the emergence of new, multi-drug resistant MDR species, resulting in increased mortality rates. Also, excessive use of antibiotics may lead to increased mortality. [ FROM AUTHOR] Copyright of Iranian Journal of Medical Microbiology is the property of Iranian Society of Microbiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
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来源期刊
Iranian Journal of Medical Microbiology
Iranian Journal of Medical Microbiology Medicine-Infectious Diseases
CiteScore
1.60
自引率
0.00%
发文量
70
审稿时长
8 weeks
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