新冠肺炎疫苗接种的免疫力及其与作为疾病严重程度指标的肺部受累严重程度的相关性

Q3 Medicine
Razieh Mousapour, Mostafa Assarroudi, Y. Khanchemehr, Masoomeh Mehrbarjou, Golmis Abdolmohammadi, Farshad Gharebakhshi, Erfan Ghanbarzadeh, Hussein Soleimantabar
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引用次数: 0

摘要

严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)大流行是一项全球性挑战;关于缺乏有效和高效的药物。看来疫苗是拯救世界免受这场大流行的唯一方式。目的:评价疫苗接种对预防COVID-19患者肺部受累及病情严重程度的影响。患者和方法:本描述性分析研究对247例2019冠状病毒病感染者进行了研究。收集人口统计学特征和疫苗接种状况信息。根据肺部受累百分比对患者的肺部计算机断层扫描结果进行评分,然后根据该评分将患者分为严重、中度、轻度和无肺部受累。通过Fisher精确检验和logistic回归评估肺部受累与疫苗接种状态之间的关系。结果:参与者以男性为主,平均年龄53.74±10.96岁。大多数人(42.9%)接种了部分疫苗。53.3%的患者有肺受累,46.6%的患者无肺受累。肺部受累与疫苗接种之间的相关性显著(P<0.001)。结论:疫苗接种是预防2019冠状病毒病严重程度的有效方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immunity due to COVID-19 vaccination and its correlation with lung involvement severity as an indicator of disease severity
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is a worldwide challenge; regarding the lack of an effective and efficient drug. It seems that the vaccine is the only modality to save the world from this pandemic. Objectives: This study was conducted to assess the effect of vaccination on preventing pulmonary involvement and the disease severity of COVID-19 patients. Patients and Methods: This descriptive-analytical study was conducted on 247 people with coronavirus disease 2019 infection. Demographic characteristics and vaccination status information were collected. Patients’ lung computed tomography scan findings were scored based on the pulmonary involvement percentage, and then according to this score, they were graded into severe, moderate, mild, and without lung involvement. The association between pulmonary involvement and vaccination status were evaluated by Fisher’s exact test and logistic regression. Results: Most participants were male, with a mean age of 53.74 ± 10.96 years. Most people (42.9%) were partial-vaccinated. Lungs in 53.3% were with lung involvement and in 46.6% were without. The correlation between pulmonary involvement and vaccination was significant (P<0.001). Conclusion: Vaccination is an effective and efficient method in preventing coronavirus disease 2019 severity.
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来源期刊
Journal of Nephropharmacology
Journal of Nephropharmacology Medicine-Pharmacology (medical)
CiteScore
1.70
自引率
0.00%
发文量
18
审稿时长
4 weeks
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