一例接受抗白细胞介素-6受体单克隆抗体治疗的升结肠癌症穿孔急诊手术后腹膜后脓肿的非典型表现和延长

Q4 Medicine

Annals of Cancer Research and Therapy Pub Date : 2019-07-30 DOI:10.4993/acrt.27.42

Toshichika Kanagawa, H. Maeda, K. Okamoto, Ian Fukudome, Sachi Tsuda, T. Namikawa, Michiya Kobayashi, K. Hanazaki

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引用次数: 2

摘要

托奇利珠单抗是一种抗白细胞介素-6受体单克隆抗体，最近被批准用于治疗炎症性关节炎和卡斯尔曼病。由于tocilizumab抑制免疫反应，非典型表现的感染更频繁发生是腹部手术后可能出现的并发症。在此，我们想描述一例在接受托西珠单抗治疗的Castleman病患者中，行癌症上行结肠穿孔手术后出现长时间腹部脓肿并伴有轻微腹部疼痛的病例。

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Atypical presentation and prolongation of retroperitoneal abscess after emergency surgery for perforated ascending colon cancer in a patient receiving anti-interleukin-6 receptor monoclonal antibody therapy

Tocilizumab is an anti-interleukin-6 receptor monoclonal antibody which was recently approved for the treatment of inflammatory arthritis and Castleman disease. Because tocilizumab suppresses immunological reactions, the more frequent occurrence of infections with atypical presentations is a conceivable complication after abdominal surgery. Herein, we would like to describe a case of a prolonged abdominal abscess with subtle abdominal pain after surgery for perforated ascending colon cancer in a patient with Castleman disease treated by tocilizumab.

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来源期刊

Annals of Cancer Research and Therapy Medicine-Pharmacology (medical)

CiteScore

0.70

自引率

0.00%

发文量