性别用药前抑制剂0.3 Mg/kgBB对抗患者插入脊柱Jar时的身体反应和患者接受

Ardi Janardika, Ezra Oktaliansyah, M. A. Prihartono
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Penelitian bersifat komparatif eksperimental dengan menggunakan uji klinis acak buta ganda terhadap 46 subjek yang dibagi acak ke dalam 2 kelompok, yaitu kelompok kontrol (kelompok C, n=23) dan kelompok premedikasi ketamin (kelompok K, n=23). Pascapemberian premedikasi ketamin dinilai respons tubuh pasien saat insersi jarum spinal menggunakan prick response score dan penerimaan pasien dengan numeric rating scale . Analisis statistik untuk respons penyuntikan dan penerimaan pasien diuji dengan tes chi-square. Hasil penelitian menunjukkan respons tubuh pasien saat insersi jarum spinal berkurang (p<0,01) dan penerimaan pasien meningkat (p<0,01) pada kelompok perlakuan. Simpulan penelitian, yaitu premedikasi ketamin 0,3 mg/kgBB yang diberikan 3 menit sebelum anestesi spinal menurunkan respons tubuh pasien saat insersi jarum spinal dan meningkatkan penerimaan pasien terhadap anestesi spinal. 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引用次数: 0

摘要

有先见之明可以减少手术前的焦虑和脊髓针插入时的身体反应。有预见性的方法可以让脊髓灰质炎在注射过程中变得更方便,合作患者减少脊髓针插入的反应。本研究的目的是确定线粒体0.3 mg/kgBB在脊髓针插入和患者接受脊髓麻醉后,对患者的身体反应进行脊髓麻醉前3分钟注射的诱导性麻醉剂的作用。这项研究是在2020年8月至12月在哈桑·萨德金·万隆的RSUP进行的。实验比较研究使用46个随机随机临床试验对象的双盲临床试验分为2组,即控制组(C, n=23)和执行K, n=23)。后牙尖针插入prick响应分数和numeric scale接收患者时,测试了氯胺酮的反应。用chi-square测试对病人反应和接受的统计分析。研究结果显示,当脊髓针注射减少(p< 0.01),患者接受增加(p< 0.01)时,身体会有反应。总结了一项研究,即在脊髓麻醉降低患者对脊髓针插入的反应前3分钟注射了0.3毫克的氯胺酮/kgBB。氯胺酮预产期0.3 mg/kgBW在脊髓针感染和满足性前可以减少脊髓针感染的先验焦虑和反应。预先考虑到为患者提供更舒适的脊髓参与,使他们在脊髓针注射期间更加合作和重复反应。这项研究的结果是确定0.3 mg/kgBW氯胺酮在脊椎针刺和满足性时的身体反应前3分钟。这项研究是8月10日由哈桑·萨德金总医院批准的。这是一种比较研究,46个主题的双盲临床试验,分为2组,一个控制组(C, n=23),和一组K, n=23)。在被氯胺酮激活后,病人的身体反应是用prick反应分数和他们的满意量表来评估脊髓针感染。在需要满足和病人满足的情况下,统计分析是使用chi square测试来评估的。研究结果表明,在脊髓针感染中,病人的身体反应被还原(p<0.01),满意性在氯胺酮预防组中增加(p<0.01)。在结果中,0.3 mg/kgBW氯胺酮中毒前3分钟,脊髓针退行性脑损伤患者在脊髓针针感染中增加满足性不足患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pengaruh Premedikasi Ketamin 0,3 Mg/kgBB terhadap Respons Tubuh Pasien Saat Insersi Jarum Spinal dan Penerimaan Pasien
Pemberian premedikasi dapat mengurangi kecemasan preoperatif dan respons tubuh pasien saat insersi jarum spinal. Premedikasi membuat intervensi spinal menjadi lebih nyaman bagi pasien, pasien kooperatif selama penyuntikan, dan mengurangi respons saat insersi jarum spinal. Tujuan penelitian ini mengetahui pengaruh premedikasi ketamin 0,3 mg/kgBB yang diberikan 3 menit sebelum dilakukan anestesi spinal terhadap respons tubuh pasien saat insersi jarum spinal dan penerimaan pasien terhadap anestesi spinal. Penelitian dilakukan periode Agustus–Desember 2020 di RSUP Dr. Hasan Sadikin Bandung. Penelitian bersifat komparatif eksperimental dengan menggunakan uji klinis acak buta ganda terhadap 46 subjek yang dibagi acak ke dalam 2 kelompok, yaitu kelompok kontrol (kelompok C, n=23) dan kelompok premedikasi ketamin (kelompok K, n=23). Pascapemberian premedikasi ketamin dinilai respons tubuh pasien saat insersi jarum spinal menggunakan prick response score dan penerimaan pasien dengan numeric rating scale . Analisis statistik untuk respons penyuntikan dan penerimaan pasien diuji dengan tes chi-square. Hasil penelitian menunjukkan respons tubuh pasien saat insersi jarum spinal berkurang (p<0,01) dan penerimaan pasien meningkat (p<0,01) pada kelompok perlakuan. Simpulan penelitian, yaitu premedikasi ketamin 0,3 mg/kgBB yang diberikan 3 menit sebelum anestesi spinal menurunkan respons tubuh pasien saat insersi jarum spinal dan meningkatkan penerimaan pasien terhadap anestesi spinal. The Effect of Ketamine Premedication 0.3 mg/kgBW before Spinal Anesthesia to Body Response during Spinal Needle Insertion and Satisfaction Premedication may reduce preoperative anxiety and response during spinal needle insertion. Premedication leads to a more comfortable spinal intervention for the patients, making them more cooperative and allaying response during spinal needle insertion. The aims of this study were to determine the effects of 0.3 mg/kgBW ketamine premedication administered 3 minutes before spinal anesthesia on the patient`s body response during spinal needle insertion and patient satisfaction. The study was conducted in August–December 2020 in Dr. Hasan Sadikin General Hospital Bandung. This was a comparative experimental study with a randomized, double blinded clinical trial on 46 subjects randomly divided into 2 groups, a control group (group C, n=23), and a ketamine premedication group (group K, n=23). After premedication with ketamine, the patient`s body response were evaluated during spinal needle insertion using the prick response score and their satisfaction using the numeric rating scale. Statistical analysis for response during needle insertion and patient satisfaction was evaluated using the chi-square test. Results of the study showed that patient`s body response during spinal needle insertion were reduced (p<0.01) and patient satisfaction was increased (p<0.01) in the ketamine premedication group. In conclusion, 0.3 mg/kgBW ketamine premedication administered 3 minutes before spinal anesthesia reduces patient body response during spinal needle insertion and increases patient satisfaction on spinal anesthesia.
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