Toward Faster Revascularization in Large Vessel Acute Ischemic Stroke: Reducing Door-to-Groin Puncture Times

Stroke treatment has evolved immensely over the past 3 decades, with mechanical thrombectomy becoming the mainstay of treatment for large vessel occlusion (LVO). In this review, we describe the progression from PROACT I to the present day, and analyze existing literature to summarize the efficacy of current methods to treat LVO. We also describe the indications for mechanical thrombectomy and the strategies that have been implemented to enhance its efficacy, including a quality improvement project conducted at the Mayo Clinic. In addition, we discuss lessons from the implementation of mechanical thrombectomy and advancements in this technique over recent years.