Thayzis d.P. Silva, A. S. Gomes, M. M. de Melo, T. M. de Oliveira, A. Galil, N. Percegoni, V. A. Fonseca, A. N. Bastos, A. S. de Aguiar
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Association of Leptin and Dried Fruit Mix and Nuts With Craving During Smoking Cessation
Objective: The objective of this study was to assess dried fruit mix and nuts and their effect on craving associated with the serum leptin of tobacco smokers. Materials and Methods: This is a clinical intervention study with a nonprobabilistic sample (n=23). The intervention group (IG) received 30 g of dried fruit and mix, and the control group (CG) received standard interventions. Test craving was analyzed using the Questionnaire of Smoking Urges (QSU-Brief). Serum leptin was assessed at the beginning and after 3 weeks. The data was tested using the SPSS program through the Shapiro-Wilk, unpaired Student t, or Mann-Whitney tests and multivariate linear regression. Results: The study showed significant difference between initial and final weights and body mass indices. The IG showed a high degree of smoking dependence. The IG showed reduced craving. In the CG, median serum leptin levels showed increased craving in the second and third weeks. Conclusions: Our results establish that craving decreased among smokers only in the IG. In the CG, above-median serum leptin levels reported a greater sense of pleasure in the second week. And in the third week, they experienced difficulties maintaining abstinence.
期刊介绍:
Addictive Disorders & Their Treatment is a quarterly international journal devoted to practical clinical research and treatment issues related to the misuses of alcohol and licit and illicit drugs and the study and treatment of addictive disorders and their behaviors. The journal publishes broad-spectrum, patient-oriented coverage of all aspects of addiction, directed toward an audience of psychiatrists, clinical psychologists, psychopharmacologists, and primary care practitioners. Original articles help clinicians make more educated, effective decisions regarding optimal patient management and care. In-depth reviews examine current understanding, diagnosis, and treatment of addiction disorders.