腹膜后肾旁去分化脂肪肉瘤伴上皮样/神经内分泌特征,生长抑素阳性。

Q4 Medicine
G. Gaggero, P. Bet, Davide Taietti, Marta Ingaliso, B. Spina
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引用次数: 0

摘要

摘要脂肪肉瘤是一种恶性间充质肿瘤,虽然来源于脂肪细胞,但也可能去分化为其他类型的细胞。我们报告一例极为罕见的上皮样/神经内分泌去分化伴生长抑素表达的肾旁腹膜后脂肪肉瘤。基于免疫形态学特征,在分子FISH检查的支持下,诊断是可能的:它显示MDM2基因扩增,这在大多数脂肪肉瘤中存在,甚至在去分化的脂肪肉瘤中也存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Retroperitoneal pararenal dedifferentiated liposarcoma with epithelioid/neuroendocrine features, somatostatin-positive.
Abstract Liposarcomas are malignant mesenchymal neoplasms that, although derived from adipocytes, may dedifferentiate to other cell types. We present an exceedingly rare case of epithelioid/neuroendocrine dedifferentiation with somatostatin expression of a pararenal retroperitoneal liposarcoma. Based on the immunomorphological features, the diagnosis was possible with the support of the molecular FISH investigation: it showed amplification of the MDM2 gene, which is present in most liposarcomas, even in dedifferentiated ones.
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来源期刊
Forum of Clinical Oncology
Forum of Clinical Oncology Medicine-Oncology
CiteScore
0.50
自引率
0.00%
发文量
3
审稿时长
6 weeks
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