Takotsubo Cardiomyopathy a Rare but Serious Complication of Treatment of Primary Central Nervous System Diffuse Large B Cell Lymphoma

Takotsubo Cardiomyopathy (TC) is a rare, temporary non-ischemic cardiomyopathy usually triggered by emotional stress or mechanical trauma of the brain, however, it might be associated with other Central Nervous System (CNS) diseases. Affected patients present with clinical symptoms of myocardial infarction, cardiac shock that may lead to cardiac arrest. Primary CNS lymphoma is also a rare disease affecting mainly elderly patients, with poor prognosis further aggravated by patient’s performance status, comorbidities, early and late treatment related complications. Here we present a 78-year-old patient with primary CNS lymphoma who unexpectedly developed TC episode following successful chemotherapy treatment.