低场便携式磁共振成像在血栓切除术后评估持续脑损伤中的应用

IF 2.1 Q3 CLINICAL NEUROLOGY
Nanthiya Sujijantarat, Andrew B. Koo, I. Jambor, A. Malhotra, Mercy H. Mazurek, Nethra R Parasuram, Vineetha Yadlapalli, Isha R Chavva, Dheeraj Lalwani, Julia Zabinska, J. M. Roy, J. Antonios, Aladine A. Elsamadicy, D. Renedo, R. Hebert, J. Schindler, E. Gilmore, L. Sansing, A. D. de Havenon, M. Olexa, S. Schiff, J. E. Iglesias, M. Rosen, W. Kimberly, N. Petersen, K. Sheth, C. Matouk
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引用次数: 0

摘要

及时的影像学检查对于接受机械取栓术(MT)的患者至关重要。我们的目的是评估低场便携式磁共振成像(pMRI)用于MT后床边评估的安全性和可行性。对疑似大血管闭塞接受MT的患者进行筛选以确定其资格。所有pMRI检查均在介入放射套件的标准铁磁环境中进行。收集临床特征、手术细节和pMRI特征。随后对72±12小时内的常规高场MRI进行分析。如果常规MRI无法进行比较,则使用同一时间段内的计算机断层扫描进行验证。纳入24例患者(63%为女性;中位年龄76岁[四分位数范围69-84岁])。MT的中位血运重建时间为15分钟(四分位数范围为8-19分钟),90%的患者脑梗死溶栓评分≥2B,结果成功。从手术结束到pMRI的中位时间为22分钟(四分位数范围为16-32分钟)。pMRI检查时间中位数为30分钟(四分位数范围17-33分钟)。在23例可获得后续成像的患者中,与MT后立即进行pMRI相比,9例患者有梗死进展,14例患者的梗死体积没有进展。未见与检查相关的不良事件。低场pMRI在MT后环境中是安全可行的,并且能够在介入放射套件中及时识别缺血性变化。这种方法可以促进基线梗死负担的评估,并可能有助于指导MT后的生理干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Low‐Field Portable Magnetic Resonance Imaging for Post‐Thrombectomy Assessment of Ongoing Brain Injury
Timely imaging is essential for patients undergoing mechanical thrombectomy (MT). Our objective was to evaluate the safety and feasibility of low‐field portable magnetic resonance imaging (pMRI) for bedside evaluation following MT. Patients with suspected large‐vessel occlusion undergoing MT were screened for eligibility. All pMRI examinations were conducted in the standard ferromagnetic environment of the interventional radiology suite. Clinical characteristics, procedural details, and pMRI features were collected. Subsequent high‐field conventional MRI within 72±12 hours was analyzed. If a conventional MRI was not available for comparison, computed tomography within the same time frame was used for validation. Twenty‐four patients were included (63% women; median age, 76 years [interquartile range, 69–84 years]). MT was performed with a median access to revascularization time of 15 minutes (interquartile range, 8–19 minutes), and with a successful outcome as defined by a thrombolysis in cerebral infarction score of ≥2B in 90% of patients. The median time from the end of the procedure to pMRI was 22 minutes (interquartile range, 16–32 minutes). The median pMRI examination time was 30 minutes (interquartile range, 17–33 minutes). Of 23 patients with available subsequent imaging, 9 had infarct progression compared with immediate post‐MT pMRI and 14 patients did not have progression of their infarct volume. There was no adverse event related to the examination. Low‐field pMRI is safe and feasible in a post‐MT environment and enables timely identification of ischemic changes in the interventional radiology suite. This approach can facilitate the assessment of baseline infarct burden and may help guide physiological interventions following MT.
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