胃癌手术中肌少症的低估价值

M. Luksta, Raminta Lukšaitė-Lukštė, A. Baušys, K. Strupas
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引用次数: 0

摘要

手术仍然是胃癌唯一潜在的治疗选择,尽管它与术后高发病率和死亡率有关。大约每两个胃癌患者中就有一个被诊断为肌肉减少症,这是术后并发症和不良长期预后的重要危险因素。然而,在常规临床实践中,肌肉减少症被低估了,因为它仍然是临床试验的兴趣。肌少症的诊断标准尚未完全标准化,但它包括肌肉力量、数量和质量的测试。它们包括握力、椅架测试、计算机断层扫描、磁共振成像、超声波、生物电阻抗分析和密度测定测试。越来越多的证据表明,肌少症对胃癌手术治疗效果的影响,肌少症的评估很有可能进入常规临床实践。尽管在此之前,还需要进一步的临床试验来规范诊断并找到有效的治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Underestimated Value of Sarcopenia in Gastric Cancer Surgery
Surgery remains the only potentially curative option for gastric cancer, although it is related to high postoperative morbidity and mortality rate. Approximately every second gastric cancer patient is diagnosed with sarcopenia, which is a significant risk factor for postoperative complications and poor long-term outcomes. However, sarcopenia is underestimated in routine clinical practice, since it remains the interest of clinical trials. Sarcopenia diagnostic criteria are not fully standardized, but it consists of tests for muscle strength, quantity and quality. They include grip strength, chair stand test, computed tomography, magnetic resonance imaging, ultrasound, bioelectrical impedance analysis and densitometry tests. Regarding the growing evidence for sarcopenia impact on surgical gastric cancer treatment results, it is a high probability that sarcopenia assessment will come to routine clinical practice. Although, until then there is a need for further clinical trials to standardize the diagnostic and to find effective treatment strategies.
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