板层孔相关视网膜前增殖的光学相干断层扫描特征

Q4 Medicine

中华眼底病杂志 Pub Date : 2019-11-25 DOI:10.3760/CMA.J.ISSN.1005-1015.2019.06.013

T. Luo, Yuzhong Cui, Xin Yang

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引用次数: 0

摘要

目的观察板层孔相关视网膜前增殖（LHEP）的OCT特征。方法回顾性分析病例。本研究纳入2013年1月至2016年12月在成都市第三人民医院眼科通过频域OCT（SD-OCT）检查诊断的128例（133眼）板层性黄斑裂孔（LMH）患者和202例（212眼）全层黄斑裂孔患者。LMH患者133眼中，LHEP患者53眼（39.8%），非LHEP患者80眼（60.2%）。在212只患有FTMH的眼睛中，有12只眼睛（5.7%）患有LHEP，200只眼睛（94.3%）没有LHEP。LMH伴或不伴LHEP患者的平均年龄分别为70.88±10.98、64.76±13.60岁。LMH伴或不伴LHEP患者的平均年龄差异具有统计学意义（U=1521.5，P=0.006）。用SD-OCT测量LMH的内径、中径和基底厚度，FTMH的高度、基底直径和最小直径。计算牵引指数（THI）和黄斑裂孔指数（MHI）。采用独立样本t检验或秩和检验比较LHEP患者和非LHEP患者LMH的内径、中位直径和基底厚度，并采用χ2检验比较椭球区损伤率。结果有或无LHEP的LMH患者，其内径分别为611.15±209.83和521.70±198.05μm，中位直径分别为961.22±571.09和497.01±172.30μm，基底厚度分别为99.83±38.69和154.12±43.17μm。LMH患者有或无LHEP时，其内径、中径和基底厚度差异有统计学意义（t=2.490、5.747、-7.395；P=0.014、0.000、0.000）。在53眼LHEP患者中，53眼中有50眼（94.34%）在椭球区受伤，80眼中有17眼（21.25%）在椭球带受伤。有或无LHEP的LMH患者的椭球区损伤率有统计学意义（χ2=68.126，P=0.000），其中12眼FTMH伴LHEP，THI＜1.0，MHI＜0.5的有10眼。结论与不加LHEP的LMH相比，加LHEP后的LMH内径和中径较大，基底较薄，椭球区损伤率较高。关键词：视网膜穿孔；层析成像、光学相干；视网膜上增殖膜

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Characteristics of optical coherence tomography of lamellar hole-associated epiretinal proliferation

Objective To observe the OCT characteristics of lamellar hole-associated epiretinal proliferation (LHEP). Methods A retrospective case analysis. A total of 128 patients (133 eyes) with lamellar macular hole (LMH) and 202 patients (212 eyes) with full-thickness macular hole (FTMH) diagnosed by the examinations of spectral-domain OCT (SD-OCT) in Department of Ophthalmology, The Third People's Hospital of Chengdu from January 2013 to December 2016 were included in this study. Among 133 eyes with LMH, there were 53 eyes (39.8%) with LHEP and 80 eyes (60.2%) without LHEP. Among 212 eyes with FTMH, there were 12 eyes (5.7%) with LHEP and 200 eyes (94.3%) without LHEP. The mean age of LMH with or without LHEP patients were 70.88±10.98, 64.76±13.60 years old, respectively. The difference of mean age between LMH with or without LHEP patients was statistically significant (U=1521.5, P=0.006). The inner diameter, median diameter and base thickness of the LMH, the height, base diameter and minimum diameter of FTMH were measured by SD-OCT. The traction index (THI) and the macular hole index (MHI) were calculated. An independent sample t-test or rank-sum test was used to compare the inner diameter, median diameter, and base thickness of the LMH in patients with or without LHEP, and χ2 test was used to compare the injury rate of ellipsoid zone. Results Of the LMH patients with or without LHEP, the inner diameter were 611.15±209.83 and 521.70±198.05 μm, the median diameter were 961.22±571.09 and 497.01±172.30 μm, the base thickness were 99.83±38.69 and 154.12±43.17 μm. The differences of the inner diameter, median diameter and the base thickness between LMH patients with or without LHEP were statistically significant (t=2.490, 5.747, -7.395; P=0.014, 0.000, 0.000). Among the 53 eyes with LHEP, There were 50 eyes (94.34%) were injured in ellipsoid zone among 53 eyes with LHEP, while 17 eyes (21.25%) were injured in ellipsoid zone among 80 eyes without LHEP. The injury rate of ellipsoid zone between LMH patients with or without LHEP was statistically significant (χ2=68.126, P=0.000). In 12 eyes of FTMH with LHEP, there were 10 eyes with THI <1.0 and MHI<0.5. Conclusion Compared with the LMH without LHEP, the LMH with LHEP has larger inner diameter and median diameter, thinner base and higher injury rate of ellipsoid zone. Key words: Retinal perforations; Tomography,optical coherence; Epiretinal proliferation membrane

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来源期刊

中华眼底病杂志 Medicine-Ophthalmology

CiteScore

0.40

自引率

0.00%

发文量

5383

期刊介绍： Chinese Journal of Ocular Fundus Diseases is the only scientific journal in my country that focuses on reporting fundus diseases. Its purpose is to combine clinical and basic research, and to give equal importance to improvement and popularization. It comprehensively reflects the leading clinical and basic research results of fundus disease disciplines in my country; cultivates professional talents in fundus disease, promotes the development of fundus disease disciplines in my country; and promotes academic exchanges on fundus disease at home and abroad. The coverage includes clinical and basic research results of posterior segment diseases such as retina, uveal tract, vitreous body, visual pathway, and internal eye diseases related to systemic diseases. The readers are medical workers and researchers related to clinical and basic research of fundus diseases. According to the journal retrieval report of the Chinese Institute of Scientific and Technological Information, the comprehensive ranking impact factor and total citation frequency of the Chinese Journal of Ocular Fundus Diseases have been among the best in the disciplines of ophthalmology, otolaryngology, and ophthalmology in my country for many years. The papers published have been included in many important databases at home and abroad, such as Scopus, Peking University Core, and China Science Citation Database (CSCD).