灵芝对超重个体的疗效：一项随机安慰剂对照试验

IF 0.7 Q4 NUTRITION & DIETETICS

Mediterranean Journal of Nutrition and Metabolism Pub Date : 2022-02-16 DOI:10.3233/mnm-211533

Shilan Babamiri, Mansooreh Sadat Mojani Qomi, M. Shiehmorteza

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引用次数: 1

摘要

背景：人们对药用蘑菇在控制超重和肥胖方面的应用越来越感兴趣。目的：本研究旨在评估灵芝对超重个体的人体测量指标、空腹血糖、血脂和血压的影响 = 25–29.9 kg/m2）接受3粒灵芝胶囊（每粒含有220 毫克整粉和30 mg纯水提取物）或匹配的安慰剂，持续6周。在治疗前后测量人体测量指标、代谢测试（空腹血糖（FBS）和血脂谱）和血压。结果：数据分析表明，干预6周后，患者的体重和BMI均有所下降（P < 0.05）。补充对某些人体测量指标有明显的有益作用。低密度脂蛋白胆固醇的变化在两个治疗组和安慰剂组之间有显著差异（P < 0.05）、FBS、其他血脂组分及血压变化不显著。结论：结果表明，灵芝可能对人体测量指标有一些潜在的益处，对脂质状况有轻微影响，但没有减肥功能的说法。因此，建议进行进一步的长期研究。

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The Efficacy of Ganoderma lucidum in Overweight Individuals: A Randomized Placebo-controlled trial

BACKGROUND: There are growing interests in the use of medicinal mushrooms in controlling overweight and obesity. OBJECTIVE: The aim of the present study was to assess the effect of Lingzhi on anthropometric indices, fasting blood sugar, lipid profile and blood pressure of overweight individuals METHODS: This randomized double-blind clinical trial was performed on seventy-two overweight individuals (Body Mass Index (BMI) = 25–29.9 kg/m2) received 3 capsule Ganoderma Lucidum (each capsule containing 220 mg of whole powder and 30 mg of pure aqueous extract) daily or matching placebo for 6 weeks. Anthropometric indices, metabolic tests (fasting blood sugar (FBS) and serum lipid profile) and blood pressure were measured before and after treatment. RESULTS: Data analyses indicated that body weight and BMI were decreased after 6-week intervention (P < 0.05). The beneficial effect of supplementation was evident on some anthropometric indices. Changes in LDL-cholesterol were significantly different between two treatment and placebo groups (P < 0.05). FBS, other components of lipid profile and blood pressure did not significantly change by Lingzi treatment. CONCLUSIONS: Results showed that Ganoderma Lucidum might have some potential benefits on anthropometric indices and mild effects on lipid profile, but and there is no claim for weight lose function. Hence, further long-term studies are recommended.

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来源期刊

Mediterranean Journal of Nutrition and Metabolism NUTRITION & DIETETICS-

CiteScore

1.70

自引率

9.10%

发文量

期刊介绍： The Mediterranean Journal of Nutrition and Metabolism publishes original scientific papers on metabolism, including diabesity and eating disorders; nutrition (epidemiological, basic, clinical and artificial); dietary and nutritional practices and management and their impact on health from prevention to treatment. The journal hosts the proceedings of relevant congresses and presents shorter notices focused on the original character of the Mediterranean nutritional civilisation. In addition, this journal is intended as a platform for scientific debate and knowledge-sharing among students and clinical practitioners, and between them and the broader scientific community, and finally as a tool for promoting and enhancing scientific cooperation.