甲状腺全切除术后甲状旁腺功能减退的评价

IF 0.1 Q4 OTORHINOLARYNGOLOGY

Bangladesh Journal of Otorhinolaryngology Pub Date : 2020-12-09 DOI:10.3329/bjo.v26i2.50612

Md Nazmul Haque, S. Khan, Moshammat Fatima Akhter, M. A. Bhuiyan, Mohammad Zakaria Sarker, M. A. Sakik

{"title":"甲状腺全切除术后甲状旁腺功能减退的评价","authors":"Md Nazmul Haque, S. Khan, Moshammat Fatima Akhter, M. A. Bhuiyan, Mohammad Zakaria Sarker, M. A. Sakik","doi":"10.3329/bjo.v26i2.50612","DOIUrl":null,"url":null,"abstract":"The most common cause of hypoparathyroidism is damage to the glands during thyroid surgery. Parathyroid gland preservation during thyroidectomy is not only desirable, but essential for the effective management of surgical diseases of the thyroid gland \nObjective: To find out the incidence rate of hypoparathyroidism after total thyroidectomy. \nMethods: Study Period: 2 years from Jan 2017 to December 2018 \nPlace of Study : National Institute of ENT, Tejgaon, Dhaka \nStudy Design: Prospective Observational Study \nSample size: 107 \nSampling Technique: Convenient Sampling technique \nResults: Among the 107 cases 39 cases were malignant comprising 36.45% of the cases. toxic multinodular goitre were 6 cases among 107 cases (5.6%) and rest 62 cases were benign multinodular goitre with or without cystic change and follicular adenomas (57.94 %). 29 cases out of 39 malignant cases were papillary carcinoma of thyroid (74.36% of malignant lesions), 2 cases of medullary Ca thyroid (5.12 % of malignant lesions) rest 8 were follicular carcinoma (20.51% of malignant lesions). 26 out of 107 (24.30%) cases suffered from postoperative hypocalcaemic tetany within 1st-5th POD. Their parathyroid hormones were significantly reduced and serum calcium were also reduced and they required calcium supplementation. In 5 (4.67%) cases there was no sign and symptoms of tetany but their serum parathormone levels were little below normal level but serum calcium levels were normal and therefore no calcium supplementation were given. The rest 76 (71.03%) cases did not show any sign or symptoms of tetany and did not require calcium supplementation. Among the patients who suffered from tetany majority were cases of Carcinoma of thyroid (18 out of 26 patients of hypoparathyroidism) 69.23%, however lateral neck dissection did not seem to affect decline in parathyroid function as 10 out of 18 patients with thyroid malignancy who suffered from postoperative tetany undergone level II to level V neck dissection in addition to total thyroidectomy. \nBangladesh J Otorhinolaryngol; October 2020; 26(2): 116-120","PeriodicalId":53915,"journal":{"name":"Bangladesh Journal of Otorhinolaryngology","volume":"26 1","pages":"116-120"},"PeriodicalIF":0.1000,"publicationDate":"2020-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Hypoparathyroidism following Total Thyroidectomy\",\"authors\":\"Md Nazmul Haque, S. Khan, Moshammat Fatima Akhter, M. A. Bhuiyan, Mohammad Zakaria Sarker, M. A. Sakik\",\"doi\":\"10.3329/bjo.v26i2.50612\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The most common cause of hypoparathyroidism is damage to the glands during thyroid surgery. Parathyroid gland preservation during thyroidectomy is not only desirable, but essential for the effective management of surgical diseases of the thyroid gland \\nObjective: To find out the incidence rate of hypoparathyroidism after total thyroidectomy. \\nMethods: Study Period: 2 years from Jan 2017 to December 2018 \\nPlace of Study : National Institute of ENT, Tejgaon, Dhaka \\nStudy Design: Prospective Observational Study \\nSample size: 107 \\nSampling Technique: Convenient Sampling technique \\nResults: Among the 107 cases 39 cases were malignant comprising 36.45% of the cases. toxic multinodular goitre were 6 cases among 107 cases (5.6%) and rest 62 cases were benign multinodular goitre with or without cystic change and follicular adenomas (57.94 %). 29 cases out of 39 malignant cases were papillary carcinoma of thyroid (74.36% of malignant lesions), 2 cases of medullary Ca thyroid (5.12 % of malignant lesions) rest 8 were follicular carcinoma (20.51% of malignant lesions). 26 out of 107 (24.30%) cases suffered from postoperative hypocalcaemic tetany within 1st-5th POD. Their parathyroid hormones were significantly reduced and serum calcium were also reduced and they required calcium supplementation. In 5 (4.67%) cases there was no sign and symptoms of tetany but their serum parathormone levels were little below normal level but serum calcium levels were normal and therefore no calcium supplementation were given. The rest 76 (71.03%) cases did not show any sign or symptoms of tetany and did not require calcium supplementation. Among the patients who suffered from tetany majority were cases of Carcinoma of thyroid (18 out of 26 patients of hypoparathyroidism) 69.23%, however lateral neck dissection did not seem to affect decline in parathyroid function as 10 out of 18 patients with thyroid malignancy who suffered from postoperative tetany undergone level II to level V neck dissection in addition to total thyroidectomy. \\nBangladesh J Otorhinolaryngol; October 2020; 26(2): 116-120\",\"PeriodicalId\":53915,\"journal\":{\"name\":\"Bangladesh Journal of Otorhinolaryngology\",\"volume\":\"26 1\",\"pages\":\"116-120\"},\"PeriodicalIF\":0.1000,\"publicationDate\":\"2020-12-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bangladesh Journal of Otorhinolaryngology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3329/bjo.v26i2.50612\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bangladesh Journal of Otorhinolaryngology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/bjo.v26i2.50612","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}

引用次数: 0

摘要

甲状旁腺功能减退症最常见的原因是甲状腺手术中的腺体损伤。甲状腺切除术中保留甲状旁腺不仅是可取的，而且对于有效治疗甲状腺外科疾病至关重要。目的：了解甲状腺全切除术后甲状旁腺功能减退的发病率。方法：研究时间：2年，自2017年1月至2018年12月研究地点：达卡特冈国家耳鼻喉科研究所研究设计：前瞻性观察研究样本量：107抽样技术：方便抽样技术结果：107例病例中39例为恶性，占36.45%。毒性多结节性甲状腺肿107例中有6例（5.6%），其余62例为良性多结节甲状腺肿伴或不伴囊性改变和滤泡腺瘤（57.94%）。39例恶性病例中29例为甲状腺乳头状癌（占恶性病变的74.36%），2例为甲状腺髓质钙癌（占肿瘤病变的5.12%），其余8例为滤泡癌（占病变的20.51%）。107例患者中有26例（24.30%）在术后第1～5个POD内出现低钙血症性破伤风。他们的甲状旁腺激素显著降低，血清钙也降低，需要补充钙。在5例（4.67%）病例中，没有破伤风的体征和症状，但他们的血清甲状旁腺激素水平略低于正常水平，但血清钙水平正常，因此没有补充钙。其余76例（71.03%）未出现任何手足口炎的体征或症状，也不需要补钙。在患有破伤风的患者中，大多数是甲状腺癌（26例甲状旁腺功能减退患者中有18例）69.23%，但侧颈清扫似乎不会影响甲状旁腺功能的下降，因为18例甲状腺恶性肿瘤患者中有10例患有术后破伤风，除全甲状腺切除术外，还接受了II至V级颈清扫。孟加拉国耳鼻喉科杂志；2020年10月；26（2）：116-120

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Evaluation of Hypoparathyroidism following Total Thyroidectomy

The most common cause of hypoparathyroidism is damage to the glands during thyroid surgery. Parathyroid gland preservation during thyroidectomy is not only desirable, but essential for the effective management of surgical diseases of the thyroid gland Objective: To find out the incidence rate of hypoparathyroidism after total thyroidectomy. Methods: Study Period: 2 years from Jan 2017 to December 2018 Place of Study : National Institute of ENT, Tejgaon, Dhaka Study Design: Prospective Observational Study Sample size: 107 Sampling Technique: Convenient Sampling technique Results: Among the 107 cases 39 cases were malignant comprising 36.45% of the cases. toxic multinodular goitre were 6 cases among 107 cases (5.6%) and rest 62 cases were benign multinodular goitre with or without cystic change and follicular adenomas (57.94 %). 29 cases out of 39 malignant cases were papillary carcinoma of thyroid (74.36% of malignant lesions), 2 cases of medullary Ca thyroid (5.12 % of malignant lesions) rest 8 were follicular carcinoma (20.51% of malignant lesions). 26 out of 107 (24.30%) cases suffered from postoperative hypocalcaemic tetany within 1st-5th POD. Their parathyroid hormones were significantly reduced and serum calcium were also reduced and they required calcium supplementation. In 5 (4.67%) cases there was no sign and symptoms of tetany but their serum parathormone levels were little below normal level but serum calcium levels were normal and therefore no calcium supplementation were given. The rest 76 (71.03%) cases did not show any sign or symptoms of tetany and did not require calcium supplementation. Among the patients who suffered from tetany majority were cases of Carcinoma of thyroid (18 out of 26 patients of hypoparathyroidism) 69.23%, however lateral neck dissection did not seem to affect decline in parathyroid function as 10 out of 18 patients with thyroid malignancy who suffered from postoperative tetany undergone level II to level V neck dissection in addition to total thyroidectomy. Bangladesh J Otorhinolaryngol; October 2020; 26(2): 116-120

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Bangladesh Journal of Otorhinolaryngology OTORHINOLARYNGOLOGY-

自引率

0.00%

发文量