650微秒1064nm激光治疗创伤

Aletha W. Tippett
{"title":"650微秒1064nm激光治疗创伤","authors":"Aletha W. Tippett","doi":"10.29011/2688-7460.100020","DOIUrl":null,"url":null,"abstract":"Objective: The objective of this paper is to present observational data to support the premise of using a 650-microsecond Nd:YAG 1064 nm laser for wound healing. Background: Laser light treatment has been reported to stimulate collagen production, the primary reason lasers are useful for cosmetic procedures such as reducing wrinkles and smoothing skin lines [1,2]. This ability to stimulate collagen, the main protein involved in wound healing, provokes the idea that a cosmetic laser could be used to promote wound healing. When working with chronic wounds, one of the main goals is to stimulate dermo-fibroblast synthesis of collagen. A demonstrated way to do this is by serial debridements, plus there are many biotech products are on the market that attempt to aid in this, in addition to, or instead of, serial debridements of the wound [3]. Cold laser therapy has actually been used for years to stimulate wound healing, but the technology has not been widely applied [3]. There have been a number of published articles on using lasers for wound healing [4-6]. Most of these use low level lasers, not cosmetic lasers, but there have been several published studies using Nd: YAG lasers for wound healing [7-9]. Multiple types of laser have been tried, especially for diabetic wound healing and have found low-energy is helpful but more research is needed [10]. The consensus from published articles is that low level laser therapy in the range of 4-8 joules/cm2 is beneficial for wound healing. Some practitioners are seeing results using multiple passes with 11 joules, but there is some study that higher laser power can be harmful to a wound by inducing scarring [7,8,11]. Having a non-invasive simple method that predictably will promote wound healing would be a boon to the millions of people suffering from various chronic wounds and for their caregivers trying to heal these wounds. Case Report The 650-microsecond Nd:YAG 1064 nm laser has been used by this writer for over 10 years for a variety of purposes, including wound stimulation. The Nd:YAG is a cosmetic laser and certainly can be used for a variety of purposes: hair removal, skin rejuvenation, scar reduction, wrinkle removal, lesion ablation, acne, etc. This laser, made by Aerolase, has a unique 650-microsecond pulse duration which enables the pulse to be delivered in a collimated beam, so that skin contact by the handpiece is not necessary (as it is with other lasers), and also it has the ability to dial in the fluence used, down all the way to 4 joules/cm2 at the lowest setting. In 2006 a report was made of using this laser on 17 wound patients over 10 weeks. All patients were treated with 4 joules/cm2, single pass. Patients were treated at various intervals. Overall, 11 or 65% of wounds improved, 3 or 18% had no change, 1 patient was lost to follow-up and 1 patient had increased pain with no improvement in the wound. A variety of wounds were treated, including pressure, neuropathic, radiation fibrosis, and burns. This retrospective look at the use of the 650-microsecond Nd:YAG 1064 nm laser for wound healing would indicate it could be an effective adjunctive instrument and deserves further study. The level of risk in doing this procedure is minimal. Proper eye protection is worn when using the laser. Laser fluence used is very low, at which level most people cannot even feel it, also there is no contact at all to the skin by the handpiece and no numbing or cooling gels that are common with most cosmetic lasers. There would be no injury or bleeding. There is no anticipated discomfort associated with the laser treatment. The anticipated benefit justifies the minimal risk involved. The 650-microsecond Nd:YAG laser could become a useful adjuvant in wound care, plus open the possibility of more studies to determine the ideal fluence to use. Because of previous preliminary work it is anticipated that patient’s wounds would heal faster than they would with available alternative approaches. Laser therapy using low fluence of 4 joules/ cm2 in one pass was used on patients with wounds. Two of these are shown here below. Citation: Tippett AW (2018) Wound Healing Therapy With a 650-Microsecond 1064nm Laser. J Family Med Prim Care Open Acc: JFOA-120. DOI: 10.29011/JFOA120. 100020 2 Volume 2018; Issue 02 One was a 37-year-old diabetic woman with burns on her feet. Because of her peripheral neuropathy she could not feel the burns when she slept with a heater. Interesting that she had seen five physicians who all told her foot needed amputation. She saw me and after taking a history, I determined she had burns and treated them appropriately. I did use the laser on her wounds and the pictures below show the beginning and after treatment. Laser therapy dramatically improved her wounds. Her wounds healed completely without scarring and one could not tell that she ever had the wounds (Figure 1). (photos courtesy of Aletha Tippett, MD) Figure 1: Laser on her wounds show treatment sites before and after treatment. A second patient was a 65-year-old man with diabetes who was diagnosed with gas gangrene of the foot and was scheduled in the hospital for amputation. I met the surgeon outside the OR and begged him to do a wide debridement instead of amputation. He agreed and did a wide debridement of the foot. The next day I started treating the wound we did use laser therapy once a week for six weeks and the pictures of beginning and after 6 weeks are shown here. Clearly the laser facilitated the healing and closure of his wound. This patient went on to totally heal his wound and was ambulatory and in fact went on a family vacation to Florida shortly thereafter (Figure 2). Figure 2: Laser therapy before therapy and after 6 weeks. Why do some wounds respond better to laser therapy than others? This is unknown by this author. Certainly burns do well and that has been seen with other burns as well. Acne responds very well to laser, but that is beyond the scope of this paper. Pressure ulcers have all responded well, but not if with radiation fibrosis. The one surgical wound presented here did well, but took six treatments. It is not clear if the area of body impacts response to laser. Conclusion Clearly it appears that use of laser (650-microsecond Nd:YAG 1064 nm) can help wound healing, and based on this clinical cases wound closure is substantially facilitated as compared to purely non-laser therapy. Giving it a trial is highly recommended. Low dose, 4 joules/cm2 seems to work very well and I would be resistant to trying higher doses as stated above. Use of this cosmetic laser for wound healing deserves further investigation.","PeriodicalId":93553,"journal":{"name":"Family medicine and primary care -- open access","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Wound Healing Therapy With a 650-Microsecond 1064nm Laser\",\"authors\":\"Aletha W. Tippett\",\"doi\":\"10.29011/2688-7460.100020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: The objective of this paper is to present observational data to support the premise of using a 650-microsecond Nd:YAG 1064 nm laser for wound healing. Background: Laser light treatment has been reported to stimulate collagen production, the primary reason lasers are useful for cosmetic procedures such as reducing wrinkles and smoothing skin lines [1,2]. This ability to stimulate collagen, the main protein involved in wound healing, provokes the idea that a cosmetic laser could be used to promote wound healing. When working with chronic wounds, one of the main goals is to stimulate dermo-fibroblast synthesis of collagen. A demonstrated way to do this is by serial debridements, plus there are many biotech products are on the market that attempt to aid in this, in addition to, or instead of, serial debridements of the wound [3]. Cold laser therapy has actually been used for years to stimulate wound healing, but the technology has not been widely applied [3]. There have been a number of published articles on using lasers for wound healing [4-6]. Most of these use low level lasers, not cosmetic lasers, but there have been several published studies using Nd: YAG lasers for wound healing [7-9]. Multiple types of laser have been tried, especially for diabetic wound healing and have found low-energy is helpful but more research is needed [10]. The consensus from published articles is that low level laser therapy in the range of 4-8 joules/cm2 is beneficial for wound healing. Some practitioners are seeing results using multiple passes with 11 joules, but there is some study that higher laser power can be harmful to a wound by inducing scarring [7,8,11]. Having a non-invasive simple method that predictably will promote wound healing would be a boon to the millions of people suffering from various chronic wounds and for their caregivers trying to heal these wounds. Case Report The 650-microsecond Nd:YAG 1064 nm laser has been used by this writer for over 10 years for a variety of purposes, including wound stimulation. The Nd:YAG is a cosmetic laser and certainly can be used for a variety of purposes: hair removal, skin rejuvenation, scar reduction, wrinkle removal, lesion ablation, acne, etc. This laser, made by Aerolase, has a unique 650-microsecond pulse duration which enables the pulse to be delivered in a collimated beam, so that skin contact by the handpiece is not necessary (as it is with other lasers), and also it has the ability to dial in the fluence used, down all the way to 4 joules/cm2 at the lowest setting. In 2006 a report was made of using this laser on 17 wound patients over 10 weeks. All patients were treated with 4 joules/cm2, single pass. Patients were treated at various intervals. Overall, 11 or 65% of wounds improved, 3 or 18% had no change, 1 patient was lost to follow-up and 1 patient had increased pain with no improvement in the wound. A variety of wounds were treated, including pressure, neuropathic, radiation fibrosis, and burns. This retrospective look at the use of the 650-microsecond Nd:YAG 1064 nm laser for wound healing would indicate it could be an effective adjunctive instrument and deserves further study. The level of risk in doing this procedure is minimal. Proper eye protection is worn when using the laser. Laser fluence used is very low, at which level most people cannot even feel it, also there is no contact at all to the skin by the handpiece and no numbing or cooling gels that are common with most cosmetic lasers. There would be no injury or bleeding. There is no anticipated discomfort associated with the laser treatment. The anticipated benefit justifies the minimal risk involved. The 650-microsecond Nd:YAG laser could become a useful adjuvant in wound care, plus open the possibility of more studies to determine the ideal fluence to use. Because of previous preliminary work it is anticipated that patient’s wounds would heal faster than they would with available alternative approaches. Laser therapy using low fluence of 4 joules/ cm2 in one pass was used on patients with wounds. Two of these are shown here below. Citation: Tippett AW (2018) Wound Healing Therapy With a 650-Microsecond 1064nm Laser. J Family Med Prim Care Open Acc: JFOA-120. DOI: 10.29011/JFOA120. 100020 2 Volume 2018; Issue 02 One was a 37-year-old diabetic woman with burns on her feet. Because of her peripheral neuropathy she could not feel the burns when she slept with a heater. Interesting that she had seen five physicians who all told her foot needed amputation. She saw me and after taking a history, I determined she had burns and treated them appropriately. I did use the laser on her wounds and the pictures below show the beginning and after treatment. Laser therapy dramatically improved her wounds. Her wounds healed completely without scarring and one could not tell that she ever had the wounds (Figure 1). (photos courtesy of Aletha Tippett, MD) Figure 1: Laser on her wounds show treatment sites before and after treatment. A second patient was a 65-year-old man with diabetes who was diagnosed with gas gangrene of the foot and was scheduled in the hospital for amputation. I met the surgeon outside the OR and begged him to do a wide debridement instead of amputation. He agreed and did a wide debridement of the foot. The next day I started treating the wound we did use laser therapy once a week for six weeks and the pictures of beginning and after 6 weeks are shown here. Clearly the laser facilitated the healing and closure of his wound. This patient went on to totally heal his wound and was ambulatory and in fact went on a family vacation to Florida shortly thereafter (Figure 2). Figure 2: Laser therapy before therapy and after 6 weeks. Why do some wounds respond better to laser therapy than others? This is unknown by this author. Certainly burns do well and that has been seen with other burns as well. Acne responds very well to laser, but that is beyond the scope of this paper. Pressure ulcers have all responded well, but not if with radiation fibrosis. The one surgical wound presented here did well, but took six treatments. It is not clear if the area of body impacts response to laser. Conclusion Clearly it appears that use of laser (650-microsecond Nd:YAG 1064 nm) can help wound healing, and based on this clinical cases wound closure is substantially facilitated as compared to purely non-laser therapy. Giving it a trial is highly recommended. Low dose, 4 joules/cm2 seems to work very well and I would be resistant to trying higher doses as stated above. Use of this cosmetic laser for wound healing deserves further investigation.\",\"PeriodicalId\":93553,\"journal\":{\"name\":\"Family medicine and primary care -- open access\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Family medicine and primary care -- open access\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.29011/2688-7460.100020\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Family medicine and primary care -- open access","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29011/2688-7460.100020","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:本文的目的是提供观测数据,以支持使用650微秒Nd:YAG 1064nm激光进行伤口愈合的前提。背景:据报道,激光治疗可以刺激胶原蛋白的产生,这是激光用于美容手术的主要原因,如减少皱纹和平滑皮肤线条[1,2]。这种刺激胶原蛋白(参与伤口愈合的主要蛋白质)的能力引发了美容激光可以用于促进伤口愈合的想法。在处理慢性伤口时,主要目标之一是刺激皮肤成纤维细胞合成胶原蛋白。一种已证明的方法是进行连续清创术,此外,除了或代替伤口的连续清创外,市场上还有许多生物技术产品试图帮助实现这一点[3]。冷激光治疗实际上已经用于刺激伤口愈合多年,但该技术尚未得到广泛应用[3]。已经发表了许多关于使用激光进行伤口愈合的文章[4-6]。其中大多数使用低水平激光,而不是美容激光,但已有几项已发表的研究使用Nd:YAG激光进行伤口愈合[7-9]。已经尝试了多种类型的激光,特别是用于糖尿病伤口愈合,并发现低能量是有帮助的,但还需要更多的研究[10]。从已发表的文章中得出的共识是,4-8焦耳/cm2范围内的低水平激光治疗有益于伤口愈合。一些从业者看到了使用11焦耳多次通过的结果,但有一些研究表明,更高的激光功率可能会导致疤痕,对伤口有害[7,8,11]。有一种非侵入性的简单方法可以预见地促进伤口愈合,这对数百万患有各种慢性伤口的人以及他们试图治愈这些伤口的护理人员来说都是一件好事。病例报告本文作者使用650微秒Nd:YAG 1064nm激光器已超过10年,用于各种目的,包括伤口刺激。Nd:YAG是一种美容激光,当然可以用于多种用途:脱毛、皮肤再生、疤痕减少、除皱、病灶消融、痤疮等。这种由Aerolase制造的激光具有独特的650微秒脉冲持续时间,可以以准直光束传输脉冲,因此不需要手持件与皮肤接触(与其他激光一样),而且它还能够在最低设置下将所使用的注量一直降低到4焦耳/cm2。2006年,一份关于在10周内对17名伤口患者使用这种激光的报告。所有患者均接受4焦耳/平方厘米的单次通过治疗。患者在不同的时间间隔接受治疗。总的来说,11%或65%的伤口得到了改善,3%或18%没有变化,1名患者失去了随访,1名病人疼痛加剧,伤口没有改善。治疗了多种伤口,包括压力性、神经性、辐射性纤维化和烧伤。对650微秒Nd:YAG 1064nm激光用于伤口愈合的回顾性研究表明,它可能是一种有效的辅助仪器,值得进一步研究。执行此程序的风险级别是最低的。使用激光时应佩戴适当的护目镜。使用的激光通量非常低,在这个水平上,大多数人甚至感觉不到,而且手机根本不会接触到皮肤,也没有大多数美容激光常见的麻木或冷却凝胶。不会有人受伤或流血。预计不会出现与激光治疗相关的不适。预期收益证明所涉及的风险最小。650微秒的Nd:YAG激光可能成为伤口护理中的一种有用的辅助手段,同时也为更多的研究确定理想的使用通量开辟了可能性。由于之前的初步工作,预计患者的伤口会比现有的替代方法愈合得更快。对有伤口的患者使用一次4焦耳/cm2的低通量激光治疗。其中两个如下所示。引文:Tippett AW(2018)用650微秒1064nm激光进行伤口愈合治疗。J Family Med Prim Care Open Acc:JFOA-120。DOI:10.29011/JFOA120。100020 2卷2018;问题02一位37岁的糖尿病妇女脚部烧伤。由于周围神经病变,当她用加热器睡觉时,她感觉不到烧伤。有趣的是,她看过五位医生,他们都告诉她脚需要截肢。她看到了我,在做了病史后,我确定她有烧伤,并进行了适当的治疗。我确实在她的伤口上使用了激光,下面的照片显示了治疗的开始和结束。激光治疗极大地改善了她的伤口。她的伤口完全愈合,没有留下疤痕,人们无法判断她是否有过伤口(图1)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Wound Healing Therapy With a 650-Microsecond 1064nm Laser
Objective: The objective of this paper is to present observational data to support the premise of using a 650-microsecond Nd:YAG 1064 nm laser for wound healing. Background: Laser light treatment has been reported to stimulate collagen production, the primary reason lasers are useful for cosmetic procedures such as reducing wrinkles and smoothing skin lines [1,2]. This ability to stimulate collagen, the main protein involved in wound healing, provokes the idea that a cosmetic laser could be used to promote wound healing. When working with chronic wounds, one of the main goals is to stimulate dermo-fibroblast synthesis of collagen. A demonstrated way to do this is by serial debridements, plus there are many biotech products are on the market that attempt to aid in this, in addition to, or instead of, serial debridements of the wound [3]. Cold laser therapy has actually been used for years to stimulate wound healing, but the technology has not been widely applied [3]. There have been a number of published articles on using lasers for wound healing [4-6]. Most of these use low level lasers, not cosmetic lasers, but there have been several published studies using Nd: YAG lasers for wound healing [7-9]. Multiple types of laser have been tried, especially for diabetic wound healing and have found low-energy is helpful but more research is needed [10]. The consensus from published articles is that low level laser therapy in the range of 4-8 joules/cm2 is beneficial for wound healing. Some practitioners are seeing results using multiple passes with 11 joules, but there is some study that higher laser power can be harmful to a wound by inducing scarring [7,8,11]. Having a non-invasive simple method that predictably will promote wound healing would be a boon to the millions of people suffering from various chronic wounds and for their caregivers trying to heal these wounds. Case Report The 650-microsecond Nd:YAG 1064 nm laser has been used by this writer for over 10 years for a variety of purposes, including wound stimulation. The Nd:YAG is a cosmetic laser and certainly can be used for a variety of purposes: hair removal, skin rejuvenation, scar reduction, wrinkle removal, lesion ablation, acne, etc. This laser, made by Aerolase, has a unique 650-microsecond pulse duration which enables the pulse to be delivered in a collimated beam, so that skin contact by the handpiece is not necessary (as it is with other lasers), and also it has the ability to dial in the fluence used, down all the way to 4 joules/cm2 at the lowest setting. In 2006 a report was made of using this laser on 17 wound patients over 10 weeks. All patients were treated with 4 joules/cm2, single pass. Patients were treated at various intervals. Overall, 11 or 65% of wounds improved, 3 or 18% had no change, 1 patient was lost to follow-up and 1 patient had increased pain with no improvement in the wound. A variety of wounds were treated, including pressure, neuropathic, radiation fibrosis, and burns. This retrospective look at the use of the 650-microsecond Nd:YAG 1064 nm laser for wound healing would indicate it could be an effective adjunctive instrument and deserves further study. The level of risk in doing this procedure is minimal. Proper eye protection is worn when using the laser. Laser fluence used is very low, at which level most people cannot even feel it, also there is no contact at all to the skin by the handpiece and no numbing or cooling gels that are common with most cosmetic lasers. There would be no injury or bleeding. There is no anticipated discomfort associated with the laser treatment. The anticipated benefit justifies the minimal risk involved. The 650-microsecond Nd:YAG laser could become a useful adjuvant in wound care, plus open the possibility of more studies to determine the ideal fluence to use. Because of previous preliminary work it is anticipated that patient’s wounds would heal faster than they would with available alternative approaches. Laser therapy using low fluence of 4 joules/ cm2 in one pass was used on patients with wounds. Two of these are shown here below. Citation: Tippett AW (2018) Wound Healing Therapy With a 650-Microsecond 1064nm Laser. J Family Med Prim Care Open Acc: JFOA-120. DOI: 10.29011/JFOA120. 100020 2 Volume 2018; Issue 02 One was a 37-year-old diabetic woman with burns on her feet. Because of her peripheral neuropathy she could not feel the burns when she slept with a heater. Interesting that she had seen five physicians who all told her foot needed amputation. She saw me and after taking a history, I determined she had burns and treated them appropriately. I did use the laser on her wounds and the pictures below show the beginning and after treatment. Laser therapy dramatically improved her wounds. Her wounds healed completely without scarring and one could not tell that she ever had the wounds (Figure 1). (photos courtesy of Aletha Tippett, MD) Figure 1: Laser on her wounds show treatment sites before and after treatment. A second patient was a 65-year-old man with diabetes who was diagnosed with gas gangrene of the foot and was scheduled in the hospital for amputation. I met the surgeon outside the OR and begged him to do a wide debridement instead of amputation. He agreed and did a wide debridement of the foot. The next day I started treating the wound we did use laser therapy once a week for six weeks and the pictures of beginning and after 6 weeks are shown here. Clearly the laser facilitated the healing and closure of his wound. This patient went on to totally heal his wound and was ambulatory and in fact went on a family vacation to Florida shortly thereafter (Figure 2). Figure 2: Laser therapy before therapy and after 6 weeks. Why do some wounds respond better to laser therapy than others? This is unknown by this author. Certainly burns do well and that has been seen with other burns as well. Acne responds very well to laser, but that is beyond the scope of this paper. Pressure ulcers have all responded well, but not if with radiation fibrosis. The one surgical wound presented here did well, but took six treatments. It is not clear if the area of body impacts response to laser. Conclusion Clearly it appears that use of laser (650-microsecond Nd:YAG 1064 nm) can help wound healing, and based on this clinical cases wound closure is substantially facilitated as compared to purely non-laser therapy. Giving it a trial is highly recommended. Low dose, 4 joules/cm2 seems to work very well and I would be resistant to trying higher doses as stated above. Use of this cosmetic laser for wound healing deserves further investigation.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信