非甾体抗炎药引起复发性过敏反应的惰性原因:全身肥大细胞增多症

IF 0.3 Q4 ALLERGY

Astim Allerji Immunoloji Pub Date : 2019-12-28 DOI:10.21911/AAI.447

G. Aytekin, S. Fındık, Fatih Çölkesen, Eray Yıldız, A. Çalışkaner

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引用次数: 0

摘要

系统性肥大细胞增多症（SM）是肥大细胞疾病的亚型之一。SM患者会出现潮红、腹部痉挛和低血压。它有时也可能导致不明原因的反复过敏发作。介质的分泌可以由多种因素触发。非甾体抗炎药（NSAIDs）因其镇痛、解热和抗炎特性而被广泛使用，是世界上最常见的处方药之一。另一方面，它们可能会引起一组不良反应，从胃炎等轻微反应到过敏反应等危及生命的过敏反应。在这篇论文中，我们报告了一名患者，他对非甾体抗炎药有多种严重不良反应，并被转诊到我们的诊所寻找安全的非甾体降压药替代品。当对她所有的系统性主诉和症状进行评估时，她最终被诊断为Indolent SM（ISM）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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An Indolent Cause of Recurrent Anaphylaxis with NSAIDs: Systemic Mastocytosis

Systemic Mastocytosis (SM) is one of the subtypes of mast cell disorders. Patients with SM suffer from flushing, abdominal cramps and hypotension. It may also cause unexplained and recurrent anaphylactic episodes sometimes. The secretion of mediators can be triggered by various factors. Non-steroidal anti-inflammatory drugs (NSAIDs) are extensively used for their analgesic, antipyretic and anti-inflammatory properties, and they are one of the most commonly prescribed drugs in the world. On the other hand, they may cause a group of adverse reactions, ranging from mild reactions like gastritis to life-threatening allergic reactions like anaphylaxis. In this paper, we report a patient who had multiple severe adverse reactions against NSAIDs and was referred to our clinic to find a safe alternative NSAID. She was eventually diagnosed with Indolent SM (ISM) when she was evaluated with all of her systemic complaints and symptoms.

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来源期刊

Astim Allerji Immunoloji ALLERGY-

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： Asthma Allergy Immunology has been published three times a year in April, August and December as the official and periodical journal of the Turkish National Society of Allergy and Clinical Immunology since 2003. All articles published in the journal have been available online since 2003. A peer reviewed system is used in evaluation of the manuscripts submitted to Asthma Allergy Immunology. The official language of the journal is English. The aim of the journal is to present advances in the field of allergic diseases and clinical immunology to the readers. In accordance with this goal, manuscripts in the format of original research, review, case report, articles about clinical and practical applications and editorials, short report and letters to the editor about allergic diseases and clinical immunology are published in the journal. The target reader population of the Asthma Allergy Immunology includes specialists and residents of allergy and clinical immunology, pulmonology, internal medicine, pediatrics, dermatology and otolaryngology as well as physicians working in other fields of medicine interested in allergy and immunological diseases.