巩膜下和结膜下Ologen的Wick技术™ 小梁切除术在高失败风险患者中的应用

Q4 Medicine
M. Rajamani, C. Ramamurthy
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引用次数: 0

摘要

简介:在小梁切除术期间,Ologen™传统上放置在结膜下,这限制了其作用区域。已经描述了在巩膜瓣下形成沟的巩膜下植入术。然而,这并不能阻止巩膜瓣边缘的纤维化。我们描述了一种改良的Ologen®放置技术,它有可能防止皮瓣边缘的疤痕,而不需要时尚的沟槽。材料与方法:本研究回顾性分析2015年1月至2016年8月间采用灯芯技术行小梁切除术联合ogen植入术的患者。判断为小梁切除术失败风险高的患者采用该技术进行手术。结果:共纳入6例患者,中位年龄38.5岁。术前平均眼压(IOP) 30.8±7.3 mmHg,术后18个月降至10.6±2.2 mmHg。术后18个月,所有患者的IOP都在十几岁左右(两名患者需要额外的局部药物治疗)。一名患者有两次低斜视发作,对类固醇和睫状体麻痹有反应。另一名患者需要两针来控制眼压。未发现其他并发症。术后3个月的超声生物显微镜检查显示1例患者有2片ogen。结论:我们的研究结果表明,该技术可以有效地用于小梁切除术失败的高风险患者。在这项技术被推荐普遍使用之前,需要在大量不同高危情况的患者中进行进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Wick technique in subscleral and subconjunctival Ologen™ implantation with trabeculectomy in patients with high risk of failure
Introduction: Ologen™ is traditionally placed subconjunctivally during trabeculectomy, which limits its area of action. Subscleral implantation of Ologen has been described involving fashioning a gutter beneath the scleral flap. This, however, would not prevent fibrosis at the margins of the scleral flap. We describe a modified technique of Ologen® placement that has the potential to prevent scarring at the margins of the flap withoutthe need to fashion a gutter. Materials and methods: The study involved a retrospective review of patients who had undergone trabeculectomy with Ologen implantation by the wick technique between January 2015 and August 2016. Patients judged to be at high risk of trabeculectomy failure were operated with this technique. Results: A total of six patients with median age of 38.5 years were included in the study. The mean preoperative intraocular pressure (IOP) was 30.8 ± 7.3 mmHg, which reduced to 10.6 ± 2.2 mmHg 18 months after surgery. By 18 months postoperative, all patients had IOP in the low teens (two patients required additional topical medication). One patient had two episodes of hypotony that responded to steroids and cycloplegics. Another patient required two needlings to bring IOP under control. No other complications were noted. Ultrasound biomicroscopy done 3 months after surgery showed two pieces of Ologen in one patient. Conclusions: The results of our study show that this technique may be used effectively in patients at high risk of trabeculectomy failure. Further studies in a larger number of patients with diverse high-risk conditions are required before this technique is recommended for general use.
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来源期刊
Asian Journal of Ophthalmology
Asian Journal of Ophthalmology Medicine-Ophthalmology
自引率
0.00%
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期刊介绍: Asian Journal of OPHTHALMOLOGY is the official peer-reviewed journal of the South East Asia Glaucoma Interest Group (SEAGIG) and is indexed in EMBASE/Excerpta Medica. Asian Journal of OPHTHALMOLOGY is published quarterly (four [4] issues per year) by Scientific Communications International Limited. The journal is published on-line only and is distributed free of cost via the SEAGIG website.
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