口腔临床直接口服抗凝血药物

Acta Medica Martiniana Pub Date : 2017-08-28 DOI:10.1515/acm-2017-0008

J. Stasko, J. Stasko, M. Janíčková, K. Mikušková, I. Malachovský, P. Gengelova, M. Kasaj, M. Smatanová, D. Statelová

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引用次数: 0

摘要

摘要直接口服抗凝药物（DOAC）在多种临床环境中通常是安全有效的，包括急性静脉血栓栓塞疾病、术后预防、非瓣膜性心房颤动患者血栓栓塞的预防以及急性冠状动脉综合征的治疗。相对较短的半衰期、快速起效和可预测的药代动力学应简化DOAC的围手术期使用。这项工作的目的是提出并总结在牙科实践中使用DOAC治疗的患者的围手术期管理，并告知这种治疗的主要规范。

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Direct Oral Anticoagulant Drugs in Dental Clinical Practice

Abstract The direct oral anticoagulant drugs (DOAC) are generally safe and effective in several clinical settings including acute venous thromboembolic disease, prophylaxis in the postoperative setting, prevention of thromboembolism in patients with non-valvular atrial fibrillation, and in the management of acute coronary syndrome. The relatively short half-life, rapid onset of action, and predictable pharmacokinetics should simplify periprocedural use of the DOAC. The aim of this work is to propose and summarize periprocedural management of patients treated with the DOAC in dental practice and to inform about the principal specifications of this treatment.

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来源期刊

Acta Medica Martiniana

自引率

0.00%

发文量

审稿时长

14 weeks

期刊介绍： Acta Medica Martiniana is a medical scientific journal, first published in print form in December 2001. It is a continuation of the journal / almanac Folia Medica Martiniana (1971 - 1996). The journal‘s owner is the Jessenius Faculty of Medicine, Comenius University, Slovakia. Dissemination of research results and scientific knowledge from all areas of medicine and nursing. Stimulation, facilitation and supporting of publication activity for the young medical research and clinical generation. The contributions of young novice authors (PhD students and post-doctorials) are particularly welcome. Acta Medica Martiniana is an open-access journal, with a periodicity of publishing three times per year (Apr/Aug/Dec). It covers a wide range of basic medical disciplines, such as anatomy, histology, biochemistry, human physiology, pharmacology, etc., as well as all clinical areas incl. preventive medicine, public health and nursing. Interdisciplinary and multidisciplinary manuscripts, including papers from all areas of biomedical research, are welcome.