Properties and Maternal and Fetal Complications in Pre-eclampsia Patients, Case Study of Sarem Women’s Hospital

Copyright© 2019, ASP Ins. This open-access article is published under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License which permits Share (copy and redistribute the material in any medium or format) and Adapt (remix, transform, and build upon the material) under the Attribution-NonCommercial terms. [1] Maternal mortality [2] Global causes of maternal death: A WHO systematic analysis [3] Public health perspectives of preeclampsia in developing countries: Implication for health system strengthening [4] The global impact of pre-eclampsia and eclampsia [5] Global burden of hypertensive disorders of pregnancy in the year 2000 [6] Prevalence of preeclampsia and eclampsia in Iran [7] Preeclampsia [8] Pijnenborg R. Pre-eclampsia [9] Risk factors and effective management of preeclampsia [10] Epidemiology of preeclampsia: impact of obesity [11] Incidence of preeclampsia: risk factors and outcomes associated with early-versus late-onset disease [12] Clinical risk factors for preeclampsia in the 21st century [13] Tobacco use during pregnancy and preeclampsia risk [14] Risk factors of pre-eclampsia/eclampsia and its adverse outcomes in low-and middle-income countries: a WHO secondary analysis [15] Clinical risk factors for pre-eclampsia determined in early pregnancy: Systematic review and meta-analysis of large cohort studies [16] Pre-eclampsia, eclampsia and adverse maternal and perinatal outcomes: A secondary analysis of the world health organization multicountry survey on maternal and newborn health [17] Short-term costs of preeclampsia to the United States health care system [18] Danforth’s obstetrics and gynecology [19] Risk of fetal death with preeclampsia [20] Maternal and neonatal outcomes in women with preeclampsia [21] Severe preeclampsia and eclampsia in Kerman, Iran: Complications and outcomes [22] Trend in admissions, clinical features and outcome of preeclampsia and eclampsia as seen from the intensive care unit of the Douala General Hospital, Cameroon [23] Prediction of adverse maternal outcomes in preeclampsia: Development and validation of the fullPIERS model [24] Abnormal liver function tests as predictors of adverse maternal outcomes in women with preeclampsia [25] Role of LDH (Lactate dehydrogenase) in preeclampsia eclampsia as a prognostic marker: An observational study [26] Accuracy of liver function tests for predicting adverse maternal and fetal outcomes in women with preeclampsia: A systematic review Aims Pre-eclampsia is one of the major cause of maternal mortality and morbidity. The aim of this study was to investigate epidemiological and fetal and maternal complications in preeclamptic patients. Materials & Methods The files of 195 patients with pre-eclampsia who were admitted to the Sarem hospital from 2010 to 2015 were investigated and information was recorded in the preprepared checklist. Findings Of the total patients, 63.9% were asymptomatic, such as loss of consciousness, epigastric pain, headache and seizure. There was no case of maternal death and only one case of intrauterine fetal death (IUFD) was available in the records. Maternal complications were observed in patients. Fetal complications were observed in 26.2% of patients. Antiphospholipid syndrome was observed in 3.1% of patients with maternal complications compared to 1% of uncomplicated mothers (p=0.001). Serum glutamic-oxaloacetic transaminase (SGOT) mean was 49.5 in mothers with complications and 26.94 in mothers without complications (p=0.043). Serum glutamic-pyruvic transaminase (SGPT) mean was 60.13 in mothers with complications compared to 23.87 in uncomplicated mothers (p=0.001). Lactate dehydrogenase (LDH) mean was 2235.38 in mothers with complications and 735.02 in mothers without complications. In patients with fetal complications LDH levels were 385.35 and in cases without fetal complications 375.02. Conclusion The level of liver enzymes and the presence of antiphospholipid syndrome are considered as predictors of maternal complications, while lactate dehydrogenase and signaling in the mother predict maternal and fetal complications. A B S T R A C T A R T I C L E I N F O