哈里亚纳邦法里达巴德balabgarh街区两个结核病单位登记的结核病患者的失访率:一项案头审查

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
Anwita Khaitan, S. Rai, A. Krishnan, S. Gupta, S. Kant, G. Khilnani
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引用次数: 0

摘要

引言:随访治疗失败(LTFU)是消除结核病的一大障碍。我们的目的是估计其在哈里亚纳邦法里达巴德地区的流行率,并了解其与选定变量的关系。材料和方法:我们对法里达巴德地区结核病中心下属的两个结核病单位的结核病通知登记册进行了案头审查。对2016年10月1日至2017年9月30日期间登记的所有患者进行分析。经过单变量分析,将P<0.2的因素纳入多变量逻辑回归模型。结果:在999名符合条件的患者中,742人(74.2%)有可用的治疗结果。LTFU估计为3.5%,累计发病率计算为每100人年6.63个LTFU。LTFU随着年龄的增长而增加。肺结核(PTB)和特发性肺结核(EPTB)患者的LTFU分别为5.2%(每100人年9.8个LTFU)和0.3%(每100人年0.6个LTFUs)。既往复发患者(9%或14.2个LTFU/100人年)和既往LTFU(16%或32个LTFU/100人年)的LTFU高于新患者中的2.4%(4.7/100人年。PTB患者和既往LTFU后接受治疗的患者的LTFU发生率分别是EPTB患者和新患者的12倍和5倍。结论:观察到的LTFU负担低于国家结核病消除计划设定的<5%的目标。缺乏有关该计划成果的信息应引起关注。在该计划下,应特别关注已确定的高危人群,以确保治疗的依从性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Loss-to-follow-up rate among tuberculosis patients registered at two tuberculosis units of ballabgarh block of district Faridabad, Haryana: A desk review
Introduction: Treatment loss-to-follow-up (LTFU) is a great obstacle to tuberculosis (TB) elimination. Our objective was to estimate its prevalence in district Faridabad, Haryana, and to see its association with selected variables. Materials and Methods: We conducted a desk review of TB notification registers of two TB units under a district TB center, Faridabad. All patients registered between October 1, 2016, and September 30, 2017, were analyzed. Following univariate analysis, factors with P < 0.2 were included in the multivariable logistic regression model. Results: Of 999 eligible patients, 742 (74.2%) had treatment outcomes available. LTFU was estimated to be 3.5%, with cumulative incidence calculated to be 6.63 LTFUs per 100 person-years. LTFU increased with increasing age. LTFU was 5.2% (9.8 LTFUs per 100 person-years) and 0.3% (0.6 LTFUs per 100 person-years) among pulmonary TB (PTB) and extra-PTB (EPTB) patients, respectively. LTFU was higher in patients with previous relapse (9% or 14.2 LTFU per 100 person-years) and previous LTFU (16% or 32 LTFUs per 100 person-years) as compared to only 2.4% (4.7 per 100 person-years) among new patients. PTB patients and patients on treatment after prior LTFU had 12 times and 5 times higher odds of LTFU than EPTB patients and new patients, respectively. Conclusion: The observed LTFU burden is lower than the <5% target set by the National TB Elimination Program. Lack of information on outcomes under the program should be cause for concern. Special attention should be paid under the program on high-risk groups identified to ensure treatment adherence.
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来源期刊
Indian Journal of Medical Specialities
Indian Journal of Medical Specialities MEDICINE, GENERAL & INTERNAL-
自引率
16.70%
发文量
51
期刊介绍: The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.
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