Anwita Khaitan, S. Rai, A. Krishnan, S. Gupta, S. Kant, G. Khilnani
{"title":"哈里亚纳邦法里达巴德balabgarh街区两个结核病单位登记的结核病患者的失访率:一项案头审查","authors":"Anwita Khaitan, S. Rai, A. Krishnan, S. Gupta, S. Kant, G. Khilnani","doi":"10.4103/injms.injms_8_23","DOIUrl":null,"url":null,"abstract":"Introduction: Treatment loss-to-follow-up (LTFU) is a great obstacle to tuberculosis (TB) elimination. Our objective was to estimate its prevalence in district Faridabad, Haryana, and to see its association with selected variables. Materials and Methods: We conducted a desk review of TB notification registers of two TB units under a district TB center, Faridabad. All patients registered between October 1, 2016, and September 30, 2017, were analyzed. Following univariate analysis, factors with P < 0.2 were included in the multivariable logistic regression model. Results: Of 999 eligible patients, 742 (74.2%) had treatment outcomes available. LTFU was estimated to be 3.5%, with cumulative incidence calculated to be 6.63 LTFUs per 100 person-years. LTFU increased with increasing age. LTFU was 5.2% (9.8 LTFUs per 100 person-years) and 0.3% (0.6 LTFUs per 100 person-years) among pulmonary TB (PTB) and extra-PTB (EPTB) patients, respectively. LTFU was higher in patients with previous relapse (9% or 14.2 LTFU per 100 person-years) and previous LTFU (16% or 32 LTFUs per 100 person-years) as compared to only 2.4% (4.7 per 100 person-years) among new patients. PTB patients and patients on treatment after prior LTFU had 12 times and 5 times higher odds of LTFU than EPTB patients and new patients, respectively. Conclusion: The observed LTFU burden is lower than the <5% target set by the National TB Elimination Program. Lack of information on outcomes under the program should be cause for concern. Special attention should be paid under the program on high-risk groups identified to ensure treatment adherence.","PeriodicalId":43811,"journal":{"name":"Indian Journal of Medical Specialities","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Loss-to-follow-up rate among tuberculosis patients registered at two tuberculosis units of ballabgarh block of district Faridabad, Haryana: A desk review\",\"authors\":\"Anwita Khaitan, S. Rai, A. Krishnan, S. Gupta, S. Kant, G. Khilnani\",\"doi\":\"10.4103/injms.injms_8_23\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Treatment loss-to-follow-up (LTFU) is a great obstacle to tuberculosis (TB) elimination. Our objective was to estimate its prevalence in district Faridabad, Haryana, and to see its association with selected variables. Materials and Methods: We conducted a desk review of TB notification registers of two TB units under a district TB center, Faridabad. All patients registered between October 1, 2016, and September 30, 2017, were analyzed. Following univariate analysis, factors with P < 0.2 were included in the multivariable logistic regression model. Results: Of 999 eligible patients, 742 (74.2%) had treatment outcomes available. LTFU was estimated to be 3.5%, with cumulative incidence calculated to be 6.63 LTFUs per 100 person-years. LTFU increased with increasing age. LTFU was 5.2% (9.8 LTFUs per 100 person-years) and 0.3% (0.6 LTFUs per 100 person-years) among pulmonary TB (PTB) and extra-PTB (EPTB) patients, respectively. LTFU was higher in patients with previous relapse (9% or 14.2 LTFU per 100 person-years) and previous LTFU (16% or 32 LTFUs per 100 person-years) as compared to only 2.4% (4.7 per 100 person-years) among new patients. PTB patients and patients on treatment after prior LTFU had 12 times and 5 times higher odds of LTFU than EPTB patients and new patients, respectively. Conclusion: The observed LTFU burden is lower than the <5% target set by the National TB Elimination Program. Lack of information on outcomes under the program should be cause for concern. Special attention should be paid under the program on high-risk groups identified to ensure treatment adherence.\",\"PeriodicalId\":43811,\"journal\":{\"name\":\"Indian Journal of Medical Specialities\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2023-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Indian Journal of Medical Specialities\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/injms.injms_8_23\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical Specialities","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/injms.injms_8_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Loss-to-follow-up rate among tuberculosis patients registered at two tuberculosis units of ballabgarh block of district Faridabad, Haryana: A desk review
Introduction: Treatment loss-to-follow-up (LTFU) is a great obstacle to tuberculosis (TB) elimination. Our objective was to estimate its prevalence in district Faridabad, Haryana, and to see its association with selected variables. Materials and Methods: We conducted a desk review of TB notification registers of two TB units under a district TB center, Faridabad. All patients registered between October 1, 2016, and September 30, 2017, were analyzed. Following univariate analysis, factors with P < 0.2 were included in the multivariable logistic regression model. Results: Of 999 eligible patients, 742 (74.2%) had treatment outcomes available. LTFU was estimated to be 3.5%, with cumulative incidence calculated to be 6.63 LTFUs per 100 person-years. LTFU increased with increasing age. LTFU was 5.2% (9.8 LTFUs per 100 person-years) and 0.3% (0.6 LTFUs per 100 person-years) among pulmonary TB (PTB) and extra-PTB (EPTB) patients, respectively. LTFU was higher in patients with previous relapse (9% or 14.2 LTFU per 100 person-years) and previous LTFU (16% or 32 LTFUs per 100 person-years) as compared to only 2.4% (4.7 per 100 person-years) among new patients. PTB patients and patients on treatment after prior LTFU had 12 times and 5 times higher odds of LTFU than EPTB patients and new patients, respectively. Conclusion: The observed LTFU burden is lower than the <5% target set by the National TB Elimination Program. Lack of information on outcomes under the program should be cause for concern. Special attention should be paid under the program on high-risk groups identified to ensure treatment adherence.
期刊介绍:
The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.