富含血小板的血浆成功治疗顽固性斑秃：一系列病例

Serbian Journal of Dermatology and Venereology Pub Date : 2019-06-01 DOI:10.2478/sjdv-2019-0007

S. Fonseka, Y.M.D.M Bandara, B. Subhani

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引用次数: 2

摘要

摘要简介。斑秃（AA）是一种引起非瘢痕性脱发的自身免疫性疾病。它通常用免疫抑制剂治疗，有些患者对此反应不佳。材料和方法。三名对标准治疗难治的AA患者每四周接受一次自体富血小板血浆（PRP）的真皮内注射治疗。后果三名患者在多次PRP治疗后均表现出显著改善。结论在许多病例报告中证明，自体PRP在治疗耐药形式的AA中是安全有效的；因此，它值得通过随机、安慰剂对照试验进行进一步研究。

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Successful Management of Treatment-Resistant Alopecia Areata with Platelet Rich Plasma: A Case Series

Abstract Introduction. Alopecia areata (AA) is an autoimmune disease-causing non-scarring alopecia. It is usually treated with immunosuppressive agents, to which some patients fail to respond adequately. Material and Methods. Three patients with AA refractory to standard therapy were treated with intra-dermal injection of autologous platelet rich plasma (PRP) every four weeks. Results. All three patients showed remarkable improvement after multiple sessions of PRP treatment. Conclusion. Autologous PRP is safe and effective in treatment-resistant forms of AA demonstrated in many case reports; therefore it deserves further study with randomized, placebo-controlled trials.

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来源期刊

Serbian Journal of Dermatology and Venereology

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期刊介绍： Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.