{"title":"血小板增多与2个月至5岁儿童下呼吸道感染严重程度的关系","authors":"B. R, S. S., D. I., D. A.","doi":"10.17727/jmsr.2023/11-17","DOIUrl":null,"url":null,"abstract":"Background: Primary or essential thrombocytosis in children is very rare but reactive thrombocytosis occurs in children and respiratory tract infection is the commonest cause. The study aimed to determine the association of thrombocytosis with severity of lower respiratory tract infection; and the association of degree of thrombocytosis with severity of pneumonia. Materials and methods: This observational study was conducted in the Department of Paediatrics of Fakhruddin Ali Ahmed Medical College & Hospital, Barpeta in Assam. This study was done on 120 children aged between 2 months and 5 years who were admitted with lower respiratory tract infection and classified according to WHO guidelines. Complete general physical examination and systemic examination with special orientation towards respiratory system was done. Complete blood count was performed with automated system sysmex xs800i cell counter. Thrombocytosis was noted and severity of thrombocytosis was classified. Results: Among 120 cases of lower respiratory tract infections, 48 children had thrombocytosis. 13 (48.1%) children with very severe disease, 29 (46.1%) children with severe pneumonia and 6(20%) children with pneumonia had thrombocytosis. Thus it was seen that there was significant association between platelet count and severity of pneumonia (p value=0.018). Two children had severe thrombocytosis (9.01-10.00L/mm3) and both of them had very severe disease. It indicates that degree of thrombocytosis increases as severity of pneumonia increases. Conclusion: There is a significant relationship between thrombocytosis and severity of pneumonia. Also degree of thrombocytosis increases as severity of pneumonia increases. Keywords: thrombocytosis; lower respiratory tract infection; pneumonia; severe pneumonia","PeriodicalId":32890,"journal":{"name":"Journal of Medical and Scientific Research","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Thrombocytosis in relation to severity of lower respiratory tract infection in children aged 2 months to 5 years\",\"authors\":\"B. R, S. S., D. I., D. A.\",\"doi\":\"10.17727/jmsr.2023/11-17\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Primary or essential thrombocytosis in children is very rare but reactive thrombocytosis occurs in children and respiratory tract infection is the commonest cause. The study aimed to determine the association of thrombocytosis with severity of lower respiratory tract infection; and the association of degree of thrombocytosis with severity of pneumonia. Materials and methods: This observational study was conducted in the Department of Paediatrics of Fakhruddin Ali Ahmed Medical College & Hospital, Barpeta in Assam. This study was done on 120 children aged between 2 months and 5 years who were admitted with lower respiratory tract infection and classified according to WHO guidelines. Complete general physical examination and systemic examination with special orientation towards respiratory system was done. Complete blood count was performed with automated system sysmex xs800i cell counter. Thrombocytosis was noted and severity of thrombocytosis was classified. Results: Among 120 cases of lower respiratory tract infections, 48 children had thrombocytosis. 13 (48.1%) children with very severe disease, 29 (46.1%) children with severe pneumonia and 6(20%) children with pneumonia had thrombocytosis. Thus it was seen that there was significant association between platelet count and severity of pneumonia (p value=0.018). Two children had severe thrombocytosis (9.01-10.00L/mm3) and both of them had very severe disease. It indicates that degree of thrombocytosis increases as severity of pneumonia increases. Conclusion: There is a significant relationship between thrombocytosis and severity of pneumonia. Also degree of thrombocytosis increases as severity of pneumonia increases. Keywords: thrombocytosis; lower respiratory tract infection; pneumonia; severe pneumonia\",\"PeriodicalId\":32890,\"journal\":{\"name\":\"Journal of Medical and Scientific Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical and Scientific Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17727/jmsr.2023/11-17\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical and Scientific Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17727/jmsr.2023/11-17","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景:儿童原发性或原发性血小板增多症非常罕见,但儿童会发生反应性血小板增多,呼吸道感染是最常见的原因。该研究旨在确定血小板增多症与下呼吸道感染严重程度的关系;以及血小板增多程度与肺炎严重程度的关系。材料和方法:这项观察性研究在阿萨姆邦Barpeta的Fakhruddin Ali Ahmed医学院和医院的儿科进行。这项研究对120名年龄在2个月至5岁之间的儿童进行,他们因下呼吸道感染入院,并根据世界卫生组织指南进行分类。对呼吸系统进行了全面的全身体检和全身检查。使用自动化系统sysmex xs800i细胞计数器进行全血计数。注意到血小板增多,并对血小板增多的严重程度进行了分类。结果:在120例下呼吸道感染病例中,48例患儿出现血小板增多症。13名(48.1%)患有非常严重疾病的儿童、29名(46.1%)患有严重肺炎的儿童和6名(20%)患有肺炎的儿童有血小板增多症。因此,血小板计数与肺炎的严重程度之间存在显著相关性(p值=0.018)。两名儿童患有严重的血小板增多症(9.01-10.00L/mm3),两人都患有非常严重的疾病。这表明血小板增多的程度随着肺炎严重程度的增加而增加。结论:血小板增多与肺炎的严重程度有显著关系。血小板增多的程度也随着肺炎的严重程度增加而增加。关键词:血小板增多症;下呼吸道感染;肺炎严重肺炎
Thrombocytosis in relation to severity of lower respiratory tract infection in children aged 2 months to 5 years
Background: Primary or essential thrombocytosis in children is very rare but reactive thrombocytosis occurs in children and respiratory tract infection is the commonest cause. The study aimed to determine the association of thrombocytosis with severity of lower respiratory tract infection; and the association of degree of thrombocytosis with severity of pneumonia. Materials and methods: This observational study was conducted in the Department of Paediatrics of Fakhruddin Ali Ahmed Medical College & Hospital, Barpeta in Assam. This study was done on 120 children aged between 2 months and 5 years who were admitted with lower respiratory tract infection and classified according to WHO guidelines. Complete general physical examination and systemic examination with special orientation towards respiratory system was done. Complete blood count was performed with automated system sysmex xs800i cell counter. Thrombocytosis was noted and severity of thrombocytosis was classified. Results: Among 120 cases of lower respiratory tract infections, 48 children had thrombocytosis. 13 (48.1%) children with very severe disease, 29 (46.1%) children with severe pneumonia and 6(20%) children with pneumonia had thrombocytosis. Thus it was seen that there was significant association between platelet count and severity of pneumonia (p value=0.018). Two children had severe thrombocytosis (9.01-10.00L/mm3) and both of them had very severe disease. It indicates that degree of thrombocytosis increases as severity of pneumonia increases. Conclusion: There is a significant relationship between thrombocytosis and severity of pneumonia. Also degree of thrombocytosis increases as severity of pneumonia increases. Keywords: thrombocytosis; lower respiratory tract infection; pneumonia; severe pneumonia