一种安全的“阿片类药物”——干针是阿片类药物的有效替代品吗?

Nicholas A Kerna, B. Tucker, R. Roberson
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引用次数: 1

摘要

中医使用针灸作为一种有效治疗多种疾病的方法已有2000多年的历史。在西方医学模式中,针灸被认为是“替代”医学。这种西方针灸模式的实践,被称为干针(DN),需要一种技术,使用单丝而不需要注射,插入软组织的不同深度——从浅层到深层——触发生理反应。某些医生和物理治疗师采用了这种西化的中医模式,使用与针灸相同的技术来进行DN和电干针(EDN)。DN和EDN通过刺激下丘脑-垂体-肾上腺轴、刺激免疫细胞和刺激视上核等多种途径介导外周、脊柱和棘上的镇痛。刺激这些部位启动阿片中间神经元机制,导致由交感神经系统和内源性大麻素介导的阿片疼痛减轻。虽然EDN进一步与脊柱到脊柱上的抗痛觉机制相关,但DN和EDN都已被证明是一个全面镇痛途径的组成部分,其作用类似于人体中的阿片类药物。在比较DN和EDN与阿片类镇痛药物使用时,不良反应及患者不良反应高的意义是必须考虑的因素;DN和EDN的不良反应明显小于阿片类药物的使用。它们具有较高的镇痛效果,其作用机制与阿片类药物相似。因此,在某些情况下,医学界应该考虑和利用DN和EDN作为阿片类药物的替代品。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A safe “opioid” – is dry needling an efficacious alternative to opioids?
Traditional Chinese medicine has used acupuncture for more than 2,000 years as a method to effectively treat numerous illnesses and diseases. It is in the Western model of medicine that acupuncture is considered ‘alternative’ medicine. The practice of this Western model of acupuncture, known as dry needling (DN), requires a technique that uses a monofilament without an injectate that is inserted into the soft tissue at varying depths–from superficial to deep–triggering a physiological response. Certain physicians and physical therapists have adopted this westernized version of the Chinese medicine modality by using the same technique for acupuncture to perform DN and electric dry needling (EDN). DN and EDN are administered to mediate analgesia peripherally, spinally, and supraspinally via multiple pathways by arousing the hypothalamic-pituitary-adrenal axis, provoking immune cells, and prompting the supraoptic nucleus. Stimulating these sites initiates the opioid interneuron mechanism resulting in opioid-based pain reduction that is mediated by the sympathetic nervous system and endogenous cannabinoids. Although EDN is further correlated with the spinal to supraspinal mechanisms of anti-nociception, both DN and EDN have shown to be components of a comprehensive analgesia pathway that acts like opioids in the human body. When comparing DN and EDN to opioid usage for analgesia, the adverse reactions and the significance of higher adverse reactions in the patient are essential factors to consider; DN and EDN have markedly less adverse effects than opioid use. They show high efficacy for analgesia and operate via similar mechanism of action as opioids. Therefore, the medical community should consider and utilize DN and EDN as an alternative to opioids in certain conditions.
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