新冠肺炎患者嗅觉功能障碍的患病率

M. Bayat, Amirmohammad Arabi, A. Assadi, Saina Nezami Nia, M. Mortezazadeh, A. Mohamadnia, N. Bahrami
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引用次数: 1

摘要

背景:如今,新冠肺炎已成为全球社会面临多重管理困难的大流行病。嗅觉功能障碍似乎是这种病毒感染的早期症状之一,许多患者在感染后才出现这种症状。考虑到这一点,嗅觉功能障碍,尤其是嗅觉下降,可能被用于筛查和防止疾病传播。方法:使用宾夕法尼亚大学针对伊朗人群的改良版嗅觉识别测试(UPSIT),即伊朗嗅觉识别测试,对50名经PCR验证的严重急性呼吸系统综合征冠状病毒2型感染参与者的嗅觉功能适足性进行评估。在这项测试中,参与者的得分与正常人群的得分进行了比较,并探讨了年龄和得分之间的可能相关性。结果:感染严重急性呼吸系统综合征冠状病毒2型的参与者在上述测试中的得分通常较低,这意味着他们的嗅觉功能下降更为显著。衰老也与嗅觉的充分性呈负相关。结论:根据本文的发现,嗅觉功能下降在严重急性呼吸系统综合征冠状病毒2型感染者中更为常见,可能是筛查计划的一个提示性指标。该指标应根据患者的年龄进行解释。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of olfactory dysfunction in COVID-19 patients
Back ground: Nowadays COVID-19 has become a pandemic in which global society experience multiple difficulties in management. It seems that olfactory dysfunction is one of the early occurring symptoms of this viral infection and many patients just show this symptom after they got infected. Considering so, olfactory dysfunction especially a decline in olfaction could potentially be used for screening purposes and preventing the disease to spread. Methods: 50 PCR-verified SARS-CoV-2 infected participants were assessed about their olfactory function adequacy using a Modified Version of the University of Pennsylvania Smell Identification Test (UPSIT) for the Iranian population called Iran Smell Identification Test (Iran-SIT). Participants scores were compared against normal population scores in this test and possible correlations of age and scores were explored as well Results: Participants with SARS-CoV-2 infection generally obtained lesser scores in the mentioned test which means they experience a decline in olfactory function more, significantly. Aging also has a negative correlation with olfaction adequacy. Conclusion: Based on this article’s finding, olfactory function decrease is more frequent among SARS-CoV-2 infected people and potentially could be a suggestive indicator for screening programs. This indicator should be interpreted concerning patients’ age.
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