ACE抑制剂和arb

Q4 Nursing

Nursing Made Incredibly Easy Pub Date : 2023-01-01 DOI:10.1097/01.nme.0000904948.57118.72

Tyler Sturdivant, Katrina Allen-Thomas

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引用次数: 1

摘要

肾素-血管紧张素-醛固酮系统(RAAS)通过调节血压(BP)、水和电解质平衡来帮助维持血流动力学稳定。该系统的不适当或异常激活可导致血管过度收缩、异常肌肉肥大和纤维化。这与许多心血管疾病有关，包括高血压、慢性心力衰竭(CHF)、心肌梗死(MI)和中风，以及糖尿病肾病等肾脏疾病。当前治疗的RAAS和药理学靶点如图1所示。

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ACE inhibitors and ARBs

The renin-angiotensin-aldosterone system (RAAS) helps maintain haemodynamic stability by regulating blood pressure (BP), water, and electrolyte balance. Inappropriate or abnormal activation of the system can lead to excessive vasoconstriction, abnormal muscular hypertrophy, and fibrosis. This is associated with many cardiovascular disorders including hypertension, chronic heart failure (CHF), myocardial infarction (MI), and stroke, and with renal disorders such as diabetic nephropathy. The RAAS and pharmacological targets for current therapies are shown in figure 1 (page 4).

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来源期刊

Nursing Made Incredibly Easy Nursing-Nurse Assisting

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： Nursing made Incredibly Easy! is based on Lippincott Williams & Wilkins"s popular and successful Incredibly Easy! book series for nurses. The emphasis of Nursing made Incredibly Easy! is on breaking down challenging clinical concepts-the ones that are often difficult or confusing to grasp-and presenting them in a refreshingly original, easily understood, and engaging format. The tone is lighthearted, but never simplistic, to make learning fun and effective. Clinical artwork mixed with humorous line drawings illustrate and reinforce key points. Articles are contributed by experienced clinicians, ensuring that content is based on sound clinical principles and hands-on expertise.