高强度间歇训练对2型糖尿病肥胖男性血清大网膜蛋白-1水平、血脂和胰岛素抵抗的影响

IF 0.6 4区 医学 Q4 ENGINEERING, BIOMEDICAL
A. S. Ahmed, Marwan Abdou Ahmed
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引用次数: 0

摘要

背景:高强度间歇训练(HIIT)是一种有效的运动方法,可使肥胖和糖尿病患者发生有利的变化。目的:研究HIIT对糖尿病肥胖男性血清大网膜蛋白1水平、脂质分布和胰岛素抵抗的影响。方法:纳入50名年龄在40至60岁之间的肥胖男性T2DM患者。受试者被分为两组:HIIT组(n=26)和对照组(n=24)。HIIT组受试者接受了为期12周(每周3次)的HIIT计划,而对照组受试对象则保持正常的日常活动。在基线和实验后评估空腹血糖水平、血清网膜蛋白-1水平、脂质状况和胰岛素抵抗。结果:HIIT显著改善了受试者的身体组成、血清网膜蛋白-1水平、脂质状况、空腹胰岛素、HOMA-IR(p<0.05)。此外,血清网膜蛋白水平与体重指数、体重和腰围之间存在高度显著的负相关。结论:12周的HIIT可能是改善糖尿病肥胖男性血清网膜蛋白-1水平、身体成分、脂质状况和胰岛素敏感性的有效训练策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of high intensity interval training on serum omentin-1 levels, lipid profile, and insulin resistance in obese men with type 2 diabetes mellitus
BACKGROUND: High-intensity interval training (HIIT) is an effective exercise method that could lead to favorable changes in obese and diabetic subjects. OBJECTIVE: To investigate the effects of HIIT on serum omentin-1 levels, lipid profile, and insulin resistance in diabetic obese men. METHODS: Fifty obese men suffering from T2DM with ages between 40 and 60 years were enrolled. Subjects were divided into two groups: the HIIT (n= 26) and control group (n= 24). The HIIT group subjects underwent 12 weeks (3 sessions per week) of HIIT program, while the control group subjects kept to their normal daily activities. Fasting blood glucose levels, serum omentin-1 levels, lipid profile, and insulin resistance were evaluated at baseline and after the experiment. RESULTS: HIIT resulted in significant improvements in the subjects’ body composition, serum omentin-1 levels, lipid profiles, fasting insulin, HOMA-IR (p< 0.05). Further, highly significant negative correlations were observed between serum omentin levels, on the one hand, and body mass index, body weight, and waist circumference, on the other. CONCLUSIONS: Twelve weeks of HIIT may be an effective training strategy to improve serum omentin-1 levels, body composition, lipid profile, and insulin sensitivity in diabetic obese men.
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来源期刊
Isokinetics and Exercise Science
Isokinetics and Exercise Science 医学-工程:生物医学
CiteScore
1.20
自引率
14.30%
发文量
37
审稿时长
>12 weeks
期刊介绍: Isokinetics and Exercise Science (IES) is an international journal devoted to the study of theoretical and applied aspects of human muscle performance. Since isokinetic dynamometry constitutes the major tool in this area, the journal takes a particular interest in exploring the considerable potential of this technology. IES publishes studies associated with the methodology of muscle performance especially with respect to the issues of reproducibility and validity of testing, description of normal and pathological mechanical parameters which are derivable from muscle testing, applications in basic research topics such as motor learning paradigms and electromyography. The journal also publishes studies on applications in clinical settings and technical aspects of the various measurement systems employed in human muscle performance research. The journal welcomes submissions in the form of research papers, reviews, case studies and technical reports from professionals in the fields of sports medicine, orthopaedic and neurological rehabilitation and exercise physiology.
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