COVID-19 during the third wave in Mexico: symptoms and vaccination as protective factor in Durango

Introduction. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was responsible for the pandemic declared in January 2020, the impact of this virus is its high transmission rate where symptoms appear 2 to 14 days after exposure in Mexico the vaccination against SARS-CoV-2 has been very important. Objective. To evaluate the frequency of SARS-CoV-2, symptoms, and the impact of vaccination in the north of Durango State during the third wave in Mexico. Material and methods. We recruited 917 subjects from Sanitary Jurisdiction #2 (dependent on the Ministry of Health of Durango state) from October 2021 to January 2022. SARS-CoV-2 was diagnosed by RT-PCR in nasopharyngeal swabs. Symptoms and vaccination were evaluated. Results. The total incidence of positive cases was 41.66% (n=382). The presence of fever, cough, anosmia and dysgeusia is positively associated with infection (p<0.05). On the other hand, previous application of the vaccine and having contact with positive subjects 14 days prior to diagnosis yielded a protective OR with respect to the disease (OR = 0.60 and 0.50, respectively) (p<0.05). Conclusions. We observed a relationship between fever, cough, anosmia and dysgeusia with the disease. On the other hand, we observed a protective factor due to vaccination.