腕管综合征合并肘管综合征的临床评分系统研究

The Hand Pub Date : 2017-01-01 DOI:10.1177/1558944716654660
Justin Koh, K. Azari, P. Benhaim
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引用次数: 1

摘要

背景:腕管和肘管综合征同时出现是一个诊断挑战,神经传导研究(NCS)在确认肘管综合征方面的局限性加剧了这一挑战。本研究开发了一种诊断评分系统,Koh-Benhaim (KB)评分,以识别合并压迫性神经病患者。方法:回顾性分析515例手术治疗腕和/或肘管松解的患者。这些患者被分为孤立型腕管综合征患者(n = 337)和合并型腕肘管综合征患者(n = 178),然后根据人口统计学、病史、体格检查和NCS结果进行特征描述。单因素和多因素logistic回归确定了合并神经病变的预测因素。综合预测因素的回归系数,构建临床评分。每次评分迭代生成受试者工作特征(ROC)曲线。计算敏感性、特异性、阳性和阴性预测值以确定最佳临界值。结果:选择固有肌力下降、尺感觉下降、屈曲试验阳性、肘管蒂内尔征阳性、NCS结果异常者。同时压迫高危的临界值为3分:阳性预测值为82.9%,特异性为93.4%。模型性能非常好,曲线下roc面积为0.917。结论:KB评分为3分或更高的患者有并发肘管压迫的高风险。所涉及的变量通常用于评估肘管,KB评分的所有组成因素在评估潜在合并压迫性神经病变患者时具有相同的临床权重。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Clinical Scoring System for Distinguishing Patients With Coincident Cubital Tunnel Syndrome Among Patients With Carpal Tunnel Syndrome
Background: Coincident carpal and cubital tunnel syndromes present a diagnostic challenge, exacerbated by the limitations of nerve conduction study (NCS) for confirming cubital tunnel syndrome. This study develops a diagnostic scoring system, the Koh-Benhaim (KB) score, to identify patients with coincident compression neuropathies. Methods: A retrospective review of 515 patients was performed from patients surgically treated for carpal and/or cubital tunnel release. These patients were divided as patients with isolated carpal tunnel syndrome (n = 337) or coincident carpal and cubital tunnel syndromes (n = 178), then characterized according to demographics, medical history, physical examination, and NCS results. Univariate and multivariate logistic regression identified predictors of coincident neuropathy. A clinical score was constructed by integerizing regression coefficients of predictive factors. Receiver operating characteristic (ROC) curves were generated for each iteration of the score. Sensitivities, specificities, and positive and negative predictive values were calculated to identify the best cutoff value. Results: Decreased intrinsic muscle strength, decreased ulnar sensation, positive elbow flexion test, positive cubital tunnel Tinel’s sign, and abnormal NCS result were selected. The cutoff value for high risk of coincident compression was 3 points: positive predictive value, 82.9% and specificity, 93.4%. Model performance was very good—ROC area under the curve of 0.917. Conclusions: A KB score of 3 or greater represents high risk of coincident cubital tunnel compression. The variables involved are routinely used to assess the cubital tunnel, and all component factors of the KB score were of equivalent clinical weight in assessing patients with potential coincident compression neuropathy.
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