强迫症患者血清维生素D水平及其相关性

Mohamed Mohamed, Ahmed Mohamed, Marwa A. El Missiry, M. Gamal
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引用次数: 0

摘要

背景和目的维生素D在钙代谢及其在增殖、分化和免疫调节中的作用中具有长期已知的关键功能。许多研究报告称,维生素D血清水平低可能是导致强迫症(OCD)发展的危险因素。本研究的目的是评估社会人口因素对维生素D的影响,并评估低维生素D的流行程度及其与强迫症的关系。患者和方法本研究收集了50名年龄在18-40岁的强迫症男性参与者的数据。使用酶联免疫吸附测定试剂盒测定本研究参与者的维生素D血清水平。结果维生素D水平与强迫症症状严重程度无显著相关性。维生素D水平低(缺乏和不足)的病例组参与者在强迫症症状和严重程度方面没有统计学上的显著差异。结论血清维生素D水平低与强迫症有一定关系。然而,维生素D血清水平、症状或强迫症的严重程度之间没有关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin D serum level and its correlation in obsessive–compulsive disorder
Background and aim Vitamin D has a long-known critical function in calcium metabolism and its role in proliferation, differentiation, and immunomodulation. A lot of studies report that low vitamin D serum level might be a risk factor contributing for the development of obsessive–compulsive disorder (OCD). The aim of this study was to evaluate the impact of sociodemographic factors on vitamin D and assess how prevalent is the hypovitaminosis D and its relation with OCD. Patients and methods In this study, data were collected from 50 participants of OCD males aged from 18 to 40 years. Vitamin D serum levels of participants in this study were measured using enzyme-linked immunosorbent assay kit. Results There is no significant relation regarding vitamin D level and OCD symptom severity found in our study. There is no statistically significant difference between participants of case group with low vitamin D levels (deficient and insufficient) in relation to OCD symptoms and severity. Conclusion There is a relation between low vitamin D serum level and OCD. However, there is no relation between vitamin D serum level, symptoms, or severity of OCD.
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