肺炎支原体感染与高密度脂蛋白代谢的研究进展

中国基层医药 Pub Date : 2020-04-01 DOI:10.3760/CMA.J.ISSN.1008-6706.2020.07.030

Luke Kong, Tingting Liu

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引用次数: 1

摘要

肺炎支原体是一种无细胞壁的革兰氏阴性菌，主要侵袭呼吸道，可造成多系统损伤。研究表明，高密度脂蛋白可以结合并中和革兰氏阴性菌细胞壁中的脂多糖和革兰氏阳性菌细胞壁中的磷酸，在病原体感染过程中抑制炎症，保护机体。由于肺炎支原体缺乏细胞壁，目前几乎没有关于肺炎支原体感染过程中高密度脂蛋白代谢变化的研究。本文就肺炎支原体感染与高密度脂蛋白代谢的研究进展作一综述。关键词:肺炎支原体;细菌;感染;细胞壁;磷壁酸;高密度脂蛋白;脂多糖;审查

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Research progress on mycoplasma pneumoniae infection and high-density lipoprotein metabolism

Mycoplasma pneumoniae is a Gram-negative bacterium without cell wall, which mainly invades the respiratory tract and also can cause multi-system damage.Studies have shown that high-density lipoprotein can bind and neutralize lipopolysaccharide in the cell wall of Gram-negative bacteria and phosphoric acid in the cell wall of Gram-positive bacteria, inhibiting inflammation and protecting the body during pathogen infection.Because mycoplasma pneumoniae lacks cell walls, there were almost no studies about high density lipoprotein metabolism changes during mycoplasma pneumoniae infection.This paper will review the research progress of mycoplasma pneumoniae infection and high-density lipoprotein metabolism. Key words: Mycoplasma pneumoniae; Bacteria; Infection; Cell wall; Teichoic acids; Lipoproteins, HDL; Lipopolysaccharides; Review

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来源期刊

中国基层医药

CiteScore

0.10

自引率

0.00%

发文量

32251

期刊介绍： Since its inception, the journal "Chinese Primary Medicine" has adhered to the development strategy of "based in China, serving the grassroots, and facing the world" as its publishing concept, reporting a large amount of the latest medical information at home and abroad, prospering the academic field of primary medicine, and is praised by readers as a medical encyclopedia that updates knowledge. It is a core journal in China's medical and health field, and its influence index (CI) ranks Q2 in China's academic journals in 2022. It was included in the American Chemical Abstracts in 2008, the World Health Organization Western Pacific Regional Medical Index (WPRIM) in 2009, and the Japan Science and Technology Agency Database (JST) and Scopus Database in 2018, and was included in the Wanfang Data-China Digital Journal Group and the China Academic Journal Comprehensive Evaluation Database.