{"title":"接种策略下多菌株SEIR流行病模型的全局稳定性","authors":"Zakaria Yaagoub, K. Allali","doi":"10.3390/mca28010009","DOIUrl":null,"url":null,"abstract":"A three-strain SEIR epidemic model with a vaccination strategy is suggested and studied in this work. This model is represented by a system of nine nonlinear ordinary differential equations that describe the interaction between susceptible individuals, strain-1-vaccinated individuals, strain-1-exposed individuals, strain-2-exposed individuals, strain-3-exposed individuals, strain-1-infected individuals, strain-2-infected individuals, strain-3-infected individuals, and recovered individuals. We start our analysis of this model by establishing the existence, positivity, and boundedness of all the solutions. In order to show global stability, the model has five equilibrium points: The first one stands for the disease-free equilibrium, the second stands for the strain-1 endemic equilibrium, the third one describes the strain-2 equilibrium, the fourth one represents the strain-3 equilibrium point, and the last one is called the total endemic equilibrium. We establish the global stability of each equilibrium point using some suitable Lyapunov function. This stability depends on the strain-1 reproduction number R01, the strain-2 basic reproduction number R02, and the strain-3 reproduction number R03. Numerical simulations are given to confirm our theoretical results. It is shown that in order to eradicate the infection, the basic reproduction numbers of all the strains must be less than unity.","PeriodicalId":53224,"journal":{"name":"Mathematical & Computational Applications","volume":"1 1","pages":""},"PeriodicalIF":1.9000,"publicationDate":"2023-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Global Stability of Multi-Strain SEIR Epidemic Model with Vaccination Strategy\",\"authors\":\"Zakaria Yaagoub, K. Allali\",\"doi\":\"10.3390/mca28010009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A three-strain SEIR epidemic model with a vaccination strategy is suggested and studied in this work. This model is represented by a system of nine nonlinear ordinary differential equations that describe the interaction between susceptible individuals, strain-1-vaccinated individuals, strain-1-exposed individuals, strain-2-exposed individuals, strain-3-exposed individuals, strain-1-infected individuals, strain-2-infected individuals, strain-3-infected individuals, and recovered individuals. We start our analysis of this model by establishing the existence, positivity, and boundedness of all the solutions. In order to show global stability, the model has five equilibrium points: The first one stands for the disease-free equilibrium, the second stands for the strain-1 endemic equilibrium, the third one describes the strain-2 equilibrium, the fourth one represents the strain-3 equilibrium point, and the last one is called the total endemic equilibrium. We establish the global stability of each equilibrium point using some suitable Lyapunov function. This stability depends on the strain-1 reproduction number R01, the strain-2 basic reproduction number R02, and the strain-3 reproduction number R03. Numerical simulations are given to confirm our theoretical results. It is shown that in order to eradicate the infection, the basic reproduction numbers of all the strains must be less than unity.\",\"PeriodicalId\":53224,\"journal\":{\"name\":\"Mathematical & Computational Applications\",\"volume\":\"1 1\",\"pages\":\"\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2023-01-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Mathematical & Computational Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/mca28010009\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATHEMATICS, INTERDISCIPLINARY APPLICATIONS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mathematical & Computational Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/mca28010009","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATHEMATICS, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
Global Stability of Multi-Strain SEIR Epidemic Model with Vaccination Strategy
A three-strain SEIR epidemic model with a vaccination strategy is suggested and studied in this work. This model is represented by a system of nine nonlinear ordinary differential equations that describe the interaction between susceptible individuals, strain-1-vaccinated individuals, strain-1-exposed individuals, strain-2-exposed individuals, strain-3-exposed individuals, strain-1-infected individuals, strain-2-infected individuals, strain-3-infected individuals, and recovered individuals. We start our analysis of this model by establishing the existence, positivity, and boundedness of all the solutions. In order to show global stability, the model has five equilibrium points: The first one stands for the disease-free equilibrium, the second stands for the strain-1 endemic equilibrium, the third one describes the strain-2 equilibrium, the fourth one represents the strain-3 equilibrium point, and the last one is called the total endemic equilibrium. We establish the global stability of each equilibrium point using some suitable Lyapunov function. This stability depends on the strain-1 reproduction number R01, the strain-2 basic reproduction number R02, and the strain-3 reproduction number R03. Numerical simulations are given to confirm our theoretical results. It is shown that in order to eradicate the infection, the basic reproduction numbers of all the strains must be less than unity.
期刊介绍:
Mathematical and Computational Applications (MCA) is devoted to original research in the field of engineering, natural sciences or social sciences where mathematical and/or computational techniques are necessary for solving specific problems. The aim of the journal is to provide a medium by which a wide range of experience can be exchanged among researchers from diverse fields such as engineering (electrical, mechanical, civil, industrial, aeronautical, nuclear etc.), natural sciences (physics, mathematics, chemistry, biology etc.) or social sciences (administrative sciences, economics, political sciences etc.). The papers may be theoretical where mathematics is used in a nontrivial way or computational or combination of both. Each paper submitted will be reviewed and only papers of highest quality that contain original ideas and research will be published. Papers containing only experimental techniques and abstract mathematics without any sign of application are discouraged.