数学模型在尼日利亚遏制COVID-19中的作用

Q2 Mathematics
C. E. Madubueze, N. M. Akabuike, Sambo Dachollom
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引用次数: 0

摘要

COVID-19是一种由严重急性呼吸综合征冠状病毒2 (SARSCoV-2)引起的病毒性疾病,目前尚无批准的疫苗。根据戴口罩、保持社交距离和封锁等现有的非药物干预措施,本工作评估了非药物控制措施(社交距离和使用口罩)和大规模检测对尼日利亚COVID-19传播的影响。通过保持社交距离、佩戴口罩等干预措施和大规模检测,建立了新型冠状病毒肺炎的数学模型。利用新一代方法计算了基本繁殖数R_0,发现当R_0< 1时,无病平衡点是局部和全局渐近稳定的。该模型使用尼日利亚的COVID-19数据进行参数化。干预措施依从性中等(50% =70%)和每日检测率较差(alpha_2 = 0,3)时,基本繁殖数均小于1 (R_0 < 1)。这意味着在这两个条件下,尼日利亚将能够阻止COVID-19的传播。然而,由于尼日利亚的检测设施和人力有限,在检测率不高的情况下,更容易强制执行严格遵守干预措施。因此,本研究主张尼日利亚政府(联邦和各州)应以实现每天至少0.3例的检测率为目标,同时确保所有公民严格遵守佩戴口罩和在公共场合保持社交距离。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Role of Mathematical Model in Curbing COVID-19 in Nigeria
COVID-19 is a viral disease that is caused by Severe Acute Respiratory Syndrome coronavirus 2 (SARSCoV-2) which has no approved vaccine. Based on the available non-pharmacological interventions like wearing of face masks, observing social distancing, and lockdown, this work assesses the impact of non-pharmaceutical control measures (social distancing and use of face-masks) and mass testing on the transmission of COVID-19 in Nigeria. A mathematical model for COVID-19 is formulated with intervention measures (observing social distancing and wearing of face masks) and mass testing. The basic reproduction number, R_0, is computed using next-generation method while the disease-free equilibrium is found to be locally and globally asymptotically stable when R_0< 1. The model is parameterized using Nigeria data on COVID-19 in Nigeria. The basic reproduction number is found to be less than unity (R_0 < 1) either when the compliance with intervention measures is moderate (50% <= alpha< 70%) and the testing rate per day is moderate (0,5 <=alpha_2 < 0,7) or when the compliance with intervention measures is strict (alpha>=70%) and the testing rate per day is poor (alpha_2 = 0,3). This implies that Nigeria will be able to halt the spread of COVID-19 under these two conditions. However, it will be easier to enforce strict compliance with intervention measures in the presence of poor testing rate due to the limited availability of testing facilities and manpower in Nigeria. Hence, this study advocates that Nigerian governments (Federal and States) should aim at achieving a testing rate of at least 0.3 per day while ensuring that all the citizens strictly comply with wearing face masks and observing social distancing in public.
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来源期刊
Communication in Biomathematical Sciences
Communication in Biomathematical Sciences Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)
CiteScore
3.60
自引率
0.00%
发文量
7
审稿时长
24 weeks
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