Mozhgan Parsaee, A. Rezaeefar, Z. Khajali, Hamideh Khesali, Mohammad Bidkhori, A. Soleimani
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引用次数: 0
摘要
背景与目的:主动脉根部扩张是法洛四联症患者的常见并发症之一。我们评估成人TFTC患者主动脉根部扩张的频率,并分析与主动脉根部扩张相关的可能危险因素。材料、方法和结果:我们回顾了1383年至1399年在Rajaie心血管医学和研究中心入院的146例成年TFTC患者的超声心动图。胸骨旁长轴位测量Valsalva窦(SOV)。主动脉根部扩张由两种定义确定。当我们根据体表面积和性别调整SOV直径时,主动脉根部扩张的频率为68%,平均SOV直径为3.5±0.7 cm,当我们使用绝对直径≥4 cm的SOV扩张时,22%的SOV出现主动脉根部扩张。通过多因素logistic回归分析,男性(优势比(OR) = 3.47, P = 0.003)、TFTC时的年龄(OR = 1.06, P = 0.009)、主动脉反流(OR = 3.97, P = 0.003)与主动脉根扩张的增加相关。3例患者接受了主动脉手术,其中1例为A型主动脉夹层。结论:虽然主动脉根部扩张是常见的,但动脉瘤扩张和不良事件并不常见。对升主动脉的所有节段(包括主动脉根)进行连续评估很重要,但并不比以前建议的更频繁。
Evaluation of aortic root dilation in adult patients after repair of tetralogy of Fallot
Background and Aim: Aortic root dilation is one of the common complications in patients with a history of tetralogy of Fallot total correction (TFTC). We evaluate the frequency of aortic root dilation in adult TFTC patients and analyze probable risk factors related to the dilated aortic root. Materials and Methods and Results: We reviewed echocardiography images of 146 adult TFTC patients who admitted at Rajaie Cardiovascular Medical and Research Center from 1383 to 1399 in an observational retrospective cohort study. Sinus of Valsalva (SOV) was measured in parasternal long-axis view. Aortic root dilation was determined by two definitions. When we adjusted SOV diameter for body surface area and sex, the frequency of aortic root dilation was 68%, with a mean SOV diameter of 3.5 ± 0.7 cm and when we used absolute diameter ≥4 cm for dilated SOV, 22% showed aortic root dilation. By multivariate logistic regression analysis, male sex (odds ratio (OR) = 3.47, P = 0.003), age at the time of TFTC (OR = 1.06, P = 0.009), and aortic regurgitation (OR = 3.97, P = 0.003) were associated with increased adds of dilated aortic root. Three patients underwent aortic surgery, including one case of type A aortic dissection. Conclusion: Although aortic root dilation was common, aneurysmal dilation and adverse events were not so frequent. Serial evaluation of all segments of the ascending aorta, including the aortic root, is important but not more frequent than previously suggested.