双相情感障碍的原发性发作

Yuriy Mysula
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引用次数: 0

摘要

背景双相情感障碍(BAD)是当代精神病学的一个热点问题。该疾病的原发性发作(PE)特征对BAD的预后、治疗和康复措施极为重要。BAD PE患者的个体心理特征尚未被探索,这使BAD的预测、治疗和预防新方法的开发变得复杂。客观的本研究的目的是调查双相情感障碍原发发作患者的个体心理特征,同时考虑性别因素和BAD首秀的临床变异。方法。对153名原发性双相情感障碍患者(65名男性和88名女性)进行了检查。根据BAD PE病程的临床变异,将患者分为三组:抑郁变异、躁狂变异和混合变异。该检查采用人格研究的标准化多因素方法(SMPR)进行。使用非参数Mann-Whitney检验对数据进行统计处理。后果SMMPR的定量指标差异最显著的是在比较抑郁和躁狂,以及BAD的抑郁和混合PE变体时,而在比较躁狂和混合变体时,差异较小。最重要的是,这些差异表现在悲观、冲动、个人主义和乐观主义方面。结论。定义了患有抑郁、躁狂和BAD PE混合变异的男性和女性患者的一些特殊特征,以促进寻找预测、治疗和预防BAD的新方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PRIMARY EPISODE OF BIPOLAR AFFECTIVE DISORDER
Background. Bipolar affective disorder (BAD) is a topical issue of contemporary psychiatry. The features of the primary episode (PE) of the disease are extremely important for prognosis, treatment and rehabilitation measures of BAD. Individual psychological features of the patients with PE of BAD are still unexplored that complicates development of new methods of prediction, treatment and prevention of BAD. Objective. The aim of the study was to investigate individual psychological features of the patients with a primary episode of bipolar affective disorder, taking into account the gender factor and clinical variant of the BAD debut. Methods. 153 patients (65 men and 88 women) with a primary episode of bipolar affective disorder were examined. The patients were divided into three groups according to the clinical variant of the course of PE of BAD: depressive variant, manic variant and mixed variant. The examination was carried out using the Standardized multifactor method of personality research (SMMPR). Statistical processing of the data was performed using the non-parametric Mann-Whitney test. Results. The most significant differences in the quantitative indicators of SMMPR were found when comparing depressive and manic, as well as depressive and mixed variants of PE of BAD, and lesser – when comparing manic and mixed variants. Most of all, these differences were expressed in terms of pessimism, impulsiveness, individualism and optimism. Conclusions. Some peculiar features of male and female patients with depressive, manic and mixed variants of PE of BAD promoting to search for new methods of prediction, treatment and prevention of BAD have been defined.
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