某三级医院收治的6个月至5岁儿童贫血的病因模式和各种临床表现的研究

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摘要

背景:营养性贫血(NA)是儿童贫血最常见的原因。缺铁是导致营养性贫血的最重要因素。严重缺铁与大脑发育受损以及认知、行为和精神运动表现有关,特别是在头两年。本研究旨在评估6个月至5岁儿童贫血的临床和病因特征。材料和方法:以医院为基础的观察性研究,对Srikakulam政府总医院收治的6个月至5岁的儿童进行研究,并根据世卫组织分类患有贫血。结果:在157名被诊断为贫血超过18个月的儿童中,缺铁性贫血是最常见的贫血原因,107名儿童出现缺铁性贫血,其次是21名儿童出现镰状细胞性贫血。在抽样的儿童中,有154名儿童康复,3名儿童死亡。结论:营养性贫血,尤其是缺铁性贫血是6个月~ 5岁儿童最常见的贫血类型。营养不良、寄生虫感染、腹泻病和复发性呼吸道感染等合并症形成恶性循环,导致营养性贫血。确定导致缺铁性贫血的因素并实施早期补铁等控制措施可降低发病率和死亡率。
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Study of etiological patterns and various clinical presentations of anemia in children aged 6 months to 5 years admitted in a tertiary care hospital
Background: Nutritional anemia (NA) is the commonest cause of anemia in children. Iron deficiency is the most important contributing factor to nutritional anemia. Severe iron deficiency is associated with impaired brain development along with cognitive, behavioural, and psychomotor manifestations, particularly during the first two years. This study aimed to evaluate the clinical and etiological profile of anemia in children aged 6 months to 5 years. Material and methods: Hospital-based observational study conducted on children between 6 months to 5 years of age, admitted to Government General Hospital, Srikakulam and having anemia according to WHO classification. Results: Of the 157 children diagnosed with anemia over 18 months period, iron deficiency anemia is the commonest cause of anemia, seen in 107 children followed by sickle cell anemia seen in 21 children. Out of the sampled children, 154 children recovered, and 3 children succumbed to death. Conclusion: Nutritional anemia, particularly iron deficiency anemia is the most common type of anemia in 6 months to 5 years-old children. Co-morbidities like malnutrition, parasitic infestations, diarrheal diseases, and recurrent respiratory tract infections form a vicious cycle and result in nutritional anemia. Identifying the factors that are leading to iron deficiency anemia and implementing the control measures like early iron supplementation results in reducing morbidity and mortality.
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