糖尿病患者神经传导试验及其他血液学参数的研究

Jasmin Parmar, Jitendra R Patel
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引用次数: 1

摘要

背景:神经传导研究(NCS)是检测糖尿病神经病变最敏感、最可靠、最无创的研究。在糖尿病神经病变中,感觉神经比运动神经受到的影响更大。了解神经传导研究有助于早期发现多发性神经病并预防其可怕的并发症。材料和方法:本研究在30名2型糖尿病患者和30名非糖尿病患者中进行。估计了HbA1c、血小板计数、凝血酶原时间、APTT、甘油三酯、LDL和HDL水平等血液学参数。记录运动神经传导速度中位数、尺神经、腓总神经和胫后神经以及感觉神经传导速度中值、尺神经和腓肠神经。结果:糖尿病患者的平均年龄为51±4.8岁。大多数受试者(86.7%)为男性。与非糖尿病患者相比,糖尿病患者的腓肠神经感觉神经传导显著减少。腓肠神经的SNCV随着糖尿病的持续时间、血糖控制不佳和患者血脂状况的改变而恶化。结论:腓肠神经传导速度检测有助于早期发现糖尿病神经病变,减轻并发症负担,提高糖尿病患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Study of Nerve Conduction Test & Other Hematological Parameters in Diabetics
Background: Nerve conduction studies (NCS) are most sensitive, reliable and non-invasive investigation to detect diabetic neuropathy. Sensory nerves are more affected as compared to motor nerves in diabetic neuropathy. Understanding the Nerve conduction studies is useful for early detection polyneuropathy and prevention of its dreaded complications. Materials and Method: The present study was conducted among 30 subjects of type 2 Diabetic and 30 non diabetics subjects. Haematological parameters such as HbA1c, platelet count, prothrombin time, APTT, triglycerides, LDL and HDL levels were estimated. Motor nerve conduction velocity median , ulnar, common peroneal and posterior tibial nerve and sensory nerve conduction velocity median , ulnar and sural nerve were recorded. Result: Mean age of diabetic patients was 51±.4.8 year. Most of the subjects (86.7%) were male. Sensory nerve conduction of sural nerve was signiicantly reduced in diabetic patients as compared to non diabetic patients. SNCV of sural nerve showed deterioration with the duration of diabetes, poor glycemic control and patients with altered lipid profile. Conclusion: Nerve conduction velocity testing of sural nerve is useful for early detection of diabetic neuropathy and reduce the burden of complication and to improve the quality of life in diabetics.
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