坦桑尼亚受伤患者与其他高危人群的HIV患病率比较

L. Barcenas, A. Tupetz, S. Behrens, A. Kozhumam, Eleanor Strand, Megan von Isenburg, Philoteus Sakasaka, M. Rubach, J. Vissoci, L. Park, J. Bettger, B. Mmbaga, C. Staton
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摘要

68%的艾滋病毒感染者生活在非洲,但只有67%的人知道自己的感染状况。急诊科(ED)可能是艾滋病病毒检测的重要入口。这项研究试图测量和比较ED损伤人群与坦桑尼亚其他临床和非临床人群的HIV流行率。在乞力马扎罗山基督教医疗中心急诊室就诊的任何严重急性损伤的成年人(≥18岁)被纳入创伤登记。进行了一项系统综述和荟萃分析,将创伤登记处的艾滋病毒流行率与其他人群进行比较。此外,759名受伤患者被纳入登记;78.6%为男性,68.2%同意接受艾滋病毒咨询和检测。HIV感染率分别为5.02%(检测)、6.25%(自我报告)和5.31%(两者均为)。该系统综述确定了在33个临床和12个非临床人群中报告HIV流行率(测试)的79项合格研究。值得注意的组包括ED损伤患者(3.53%,95%置信区间)、多发性损伤患者(10.67%,95%置信度)和注射药物的人(17.43%,95%可信区间)。这些发现表明,与普通人群相比,ED损伤患者可能面临更高的艾滋病毒风险,ED是增加年轻人(尤其是男性)艾滋病毒检测的潜在途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
HIV Prevalence among Injury Patients Compared to Other High-Risk Groups in Tanzania
Sixty-eight percent of persons infected with HIV live in Africa, but as few as 67% of those know their infection status. The emergency department (ED) might be a critical access point to HIV testing. This study sought to measure and compare HIV prevalence in an ED injury population with other clinical and nonclinical populations across Tanzania. Adults (≥18 years) presenting to Kilimanjaro Christian Medical Center ED with acute injury of any severity were enrolled in a trauma registry. A systematic review and meta-analysis was conducted to compare HIV prevalence in the trauma registry with other population groups. Further, 759 injury patients were enrolled in the registry; 78.6% were men and 68.2% consented to HIV counseling and testing. The HIV prevalence was 5.02% (tested), 6.25% (self-report), and 5.31% (both). The systematic review identified 79 eligible studies reporting HIV prevalence (tested) in 33 clinical and 12 nonclinical population groups. Notable groups included ED injury patients (3.53%, 95% CI), multiple injury patients (10.67%, 95% CI), and people who inject drugs (17.43%, 95% CI). These findings suggest that ED injury patients might be at higher HIV risk compared to the general population, and the ED is a potential avenue to increasing HIV testing among young adults, particularly men.
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