与年龄相关的超声乳腺密度模式:对乳腺癌症风险的意义

IF 0.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
N. Irurhe, N. Ibeabuchi, O. Olowoyeye, O. Ihekuna, O. Balogun, Caleb Yakubu, F. Duru
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引用次数: 0

摘要

简介:乳腺/乳腺密度很重要,因为它是乳腺癌风险的已知生物标志物。然而,乳房x光检查的敏感性随着年龄越小乳腺密度越高而降低。超声被认为是乳腺密度分类和乳腺病变发现和表征的一线检查。本研究旨在探讨年龄与超声乳腺密度的关系及其对乳腺癌风险的影响。材料和方法:这是一项基于社区的横断面、探索性、描述性研究,涉及658名女性。乳房超声扫描使用Sonoace X1机器与7.5 MHz换能器进行。超声检查发现病变为良性或恶性后,进一步行细胞病理学检查。结果:33 ~ 43岁年龄组占29.8%。超声乳腺密度型与年龄有显著的相关性(P<0.01), <33岁年龄组以纤维腺密度型为主,多为良性病变,而33 - 53岁年龄组以异质性乳腺密度型为主,多为恶性病变,是乳腺癌的高危人群。结论:年龄与超声检查乳腺密度成反比关系,并非绝对关系。超声在乳腺病变的诊断过程中是一种可靠的筛查工具,作为一种影像学工具,在致密乳腺中是首选的检查方式。异质纤维腺型成为乳腺癌的高危人群,尤其是中年人。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Age-related ultrasonographic mammary gland density patterns: Implication for breast cancer risk
Introduction: Mammary gland/breast density is important because it is a known biomarker for breast cancer risk. However, the sensitivity of mammography decreases with high breast density found in younger age group. Ultrasound is considered as the first-line examination in the classification of breast density and in the detection and characterization of breast lesions. This study aims to evaluate the relationship between age and ultrasonographic breast density pattern and its implication for breast cancer risk. Materials and Methods: This was a community-based cross-sectional, exploratory, descriptive study involving 658 females. Breast ultrasonographic scans were performed using a Sonoace X1 Machine with a 7.5 MHz transducer. The lesions detected and classified by ultrasonography as benign or malignant were further subjected to cytopathology. Results: Modal age group of the participants ranged from 33 to 43 years representing 29.8%. There was significant correlation (P<0.01) between ultrasonographic mammary gland density pattern and age, the age group of <33 years demonstrated predominant fibroglandular density pattern with mostly benign lesions, while the age group of 33–53 years demonstrated predominant heterogeneous breast density pattern with most of the malignant lesions in this age group, making it the high-risk group for breast cancer. Conclusion: The relationship between age and ultrasonographic breast density is inversely proportional and not absolute. It also concludes that ultrasonography is a reliable screening tool in the diagnostic process for mammary gland lesions, and as an imaging tool, it is the preferred modality in dense breast. The heterogeneous fibroglandular pattern emerged as the high-risk group for breast cancer, especially in middle age.
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来源期刊
West African Journal of Radiology
West African Journal of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
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