鲶鱼辣木粉纳米液体食品配方对大鼠氧化应激及减少烧伤大小的影响

Utari Yunitaningrum, C. Kusharto, Katrin Roosita
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引用次数: 0

摘要

烧伤引起的高分解代谢和炎症反应会影响自由基的增加,从而导致氧化应激状态,从而延迟伤口的愈合过程。提供蛋白质有助于改善分解代谢过程中蛋白质的损失,对于抗氧化剂来说,它们可以防止氧化应激情况的发生。蛋白质和抗氧化剂来源的一种产品是由鲶鱼和辣木面粉制成的液体食品配方,这些面粉是用纳米技术加工的。本研究旨在分析用纳米技术加工的鲶鱼和辣木粉制成的液体食品配方对烧伤Sprague-Dawley大鼠的影响,特别是对丙二醛水平和减少伤口面积的影响。本研究的设计是一项实验研究,共有6个实验组,即给予最水干预的大鼠(K)、15%液体食品配方(MCB 15)、30%液体食物配方(MCB 30)、15%纳米液体食品(MCN 15)和30%纳米液体食物(MCN 30)14天。单向方差分析表明,所有实验组的丙二醛水平没有显著差异。然而,丙二醛水平的最高下降发生在MCN30组。此外,MCN 30组也显示出伤口面积的最大减少,并且与对照组MCB 15、MCN 15和MCK 30显著不同,但基于单向方差分析检验和Duncan的进一步检验,与MCB 30组没有显示出显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Nano Liquid Food Formula Made from Catfish and Moringa Flours on Oxidative Stress and Reduction of Burn Size in Rats
The high catabolism and inflammatory responses due to the burn injury can affect the increase of free radicals resulting in oxidative stress condition that delays the healing process of wounds. Providing protein can help to improve protein loss during catabolism, as for antioxidants, they prevent the occurrence of oxidative stress situation. One product of protein and antioxidants source that have been developed is a liquid food formula made from Catfish and Moringa flour which were processed using nanotechnology. This study aims to analyze the effect of liquid food formula made from Catfish and Moringa flour processed using nanotechnology on Sprague Dawley rats with burn injury, especially on malondialdehyde levels and reduction in wound area. The design of this study was an experimental study with 6 experimental groups, namely rats with aquadest intervention (K), 15% liquid food formula (MCB 15), 30% liquid food formula (MCB 30), 15% nano liquid food (MCN 15), and 30% nano liquid food (MCN 30) that given for 14 days. The One Way ANOVA test indicated that there was no significant difference in malondialdehyde levels among all experimental groups. However, the highest decrease in malondialdehyde levels occurred in the MCN 30 group. Moreover, the MCN 30 group also showed the highest reduction in the wound area and was significantly different from the control group, MCB 15, MCN 15, and MCK 30, but didn’t show a significant difference from the MCB 30 group based on the One Way ANOVA test and a further test of Duncan.
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