Severe Fever with Thrombocytopenia Syndrome Virus: The First Case Report in Thailand

her red blood cell (RBC) was 20 per microliter, there was no pleocytosis, mildly elevated protein level (67 mg/dl) and normal glucose level. Bacterial culture of CSF yielded had no growth. CSF polymerase chain reaction (PCR) for viral panel was negative. Later, she was referred to Phyathai 3 Hospital. From febrile of 39°C. The level of consciousness had decreased (Glasgow Coma Score of 9) and she had apparent neck stiffness on physical examination. Motor power was at least grade 3 with a spastic tone of all extremities. An electroencephalogram (EEG) was done. The background activity was moderately slow, indicating the patient had encephalopathy. There was no epileptiform discharge. The laboratory results were remarkable for leukopenia (white blood cell count was 2,100 cells/mm 3 with 45% neutrophils and 50% lymphocytes), and thrombocytopenia (platelet count was 88,000/mm3). High D-dimer (2.96 ug/ml), coagulopathy and peripheral blood smear showed decreased number of platelets, few schistocytes, few polychromasia compatible with Abstract We report a case of a 70-year-old Thai woman with severe fever and thrombocytopenia syndrome, who had lost all seven of her cats from sickness over a week. Diagnosis was established by the detection of viral RNA in serum via real-time polymerase chain reaction. Her symptoms improved after taking doxycycline orally and supportive treatment.