儿童自身免疫性脑炎和自身炎症/自身免疫相关癫痫癫痫发作的治疗机制和新兴疗法。

IF 2.6 4区医学 Q2 RHEUMATOLOGY

Rheumatic Disease Clinics of North America Pub Date : 2023-08-28 DOI:10.1016/j.rdc.2023.06.010

Milena M. Andzelm MD, PhD , Coral M. Stredny MD

引用次数: 0

摘要

人们越来越了解炎症在癫痫发作和癫痫中的作用，以及有针对性的免疫调节治疗。在儿童中，免疫介导的癫痫发作通常在自身免疫性脑炎的情况下急性出现，并且对免疫疗法反应非常灵敏，随后的癫痫发生率很低。相反，自身免疫相关癫痫的癫痫发作，如Rasmussen综合征，对包括免疫调节在内的多模式治疗仍然是难治的。在这篇综述中，作者讨论了儿童免疫介导的癫痫发作的表现、潜在机制和新兴疗法。

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Mechanisms and Emerging Therapies for Treatment of Seizures in Pediatric Autoimmune Encephalitis and Autoinflammatory/Autoimmune-Associated Epilepsy

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来源期刊

Rheumatic Disease Clinics of North America 医学-风湿病学

CiteScore

4.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Rheumatic Disease Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Each issue (February, May, August, and November) focuses on a single topic in rheumatology and is presented under the direction of an experienced editor. Topics include osteoarthritis, rheumatoid arthritis, crystal diseases, MSK exam, disorders of the bone, immunodeficiency states, lupus, neuromuscular disease, pain disorders, scleroderma, vasculitis, pediatrics, therapeutics, treatment guidelines, and treatment modalities.