小儿新克罗恩病。

IF 4.5 3区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Inflammatory Bowel Diseases Pub Date : 2024-09-03 DOI:10.1093/ibd/izad231

Delia O'Shea, Joseph A Picoraro

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引用次数: 0

摘要

接受回肠袋-肛门吻合术（IPAA）治疗难治性溃疡性结肠炎（UC）的儿童可能最终发展为克罗恩病（CD）表型。这种全新的CD容易被广泛解读和错误归因，人们对其在儿童身上的表现知之甚少。手术改变的回肠小袋环境有患一系列回肠小袋疾病的风险，儿童对此的描述有限。在本期《炎症性肠病》中，一项针对接受IPAA并发展为新发CD的UC儿童的多中心回顾性研究强调了儿童回肠袋特征的挑战和机遇。

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De Novo Crohn's Disease in the Pediatric Pouch.

Children who undergo ileal pouch anal anastomosis (IPAA) surgery for refractory ulcerative colitis (UC) may ultimately develop a Crohn's disease (CD) phenotype. This de novo CD is open to broad interpretation and misattribution, and its manifestation in children is poorly understood. The surgically altered environment of the ileal pouch is at risk of a spectrum of ileal pouch disorders, which have limited description in children. In this issue of Inflammatory Bowel Diseases, a multicenter, retrospective study of children with UC who underwent IPAA and developed de novo CD highlights the challenges and opportunities of ileal pouch characterization in children.

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来源期刊

Inflammatory Bowel Diseases 医学-胃肠肝病学

CiteScore

9.70

自引率

6.10%

发文量

462

审稿时长

1 months

期刊介绍： Inflammatory Bowel Diseases® supports the mission of the Crohn''s & Colitis Foundation by bringing the most impactful and cutting edge clinical topics and research findings related to inflammatory bowel diseases to clinicians and researchers working in IBD and related fields. The Journal is committed to publishing on innovative topics that influence the future of clinical care, treatment, and research.