小型经皮肾切开取石术:对于神经源性膀胱患者来说,较小的肾结石更好吗?

IF 0.8 4区 医学 Q4 UROLOGY & NEPHROLOGY
Progres En Urologie Pub Date : 2024-01-01 Epub Date: 2023-09-26 DOI:10.1016/j.purol.2023.09.009
C Bouteille, M Pere, I Chelghaf, J Rigaud, F X Madec, M-A Perrouin-Verbe, T Loubersac
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引用次数: 0

摘要

引言:患有神经性膀胱的患者患尿石症的风险增加,目前,在这一人群中进行小型经皮肾取石术的数据有限。我们的目的是比较迷你(15F)经皮肾取石术、标准(24F)PCNL和柔性输尿管镜在治疗神经源性下尿路功能障碍(NLUTD)患者肾结石方面的疗效和安全性。纳入了2005年至2020年间接受过提取手术的所有连续NLUTD患者和肾下肾盏累计结石大小大于15mm或10mm的患者。主要终点是CT扫描3个月时的一次结石清除率(SFR)。次要终点是并发症(Clavien-Dindo分级系统)、手术时间、失血量和住院时间。结果:我们进行了76次标准PCNL(sPCNL)、46次柔性输尿管镜碎石术(fURL)和25次小型化PCNL(mPCNL)。mPCNL组、sPCNL组和fURL组的一次疗程SFR分别为37.5%、38.2%和37%,三种手术之间无显著差异(P=0.99)。mPCNL、sPCNL和fURL第二次干预后的最终SFR分别为48%、61.8%和63%(P=0.67)。结论:mPCNL治疗NLUTD的疗效与其他技术没有差异,但并发症发生率明显低于sPCNL。证明级别:3。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Mini-percutaneous nephrolithotomy: Is smaller better for kidney stones in patients with neurogenic bladder?

Introduction: Patients with neurologic bladder are at an increased risk for urolithiasis, and currently, data on mini-percutaneous nephrolithotomy in this population are limited. Our objective was to compare mini (15F)-percutaneous nephrolithotomy, standard (24F)-PCNL and flexible ureteroscopy in terms of efficacy and safety in treatment of kidney stones in patients with neurogenic lower urinary tract dysfunction (NLUTD).

Methods: We conducted a retrospective monocentric study in our neuro-urological referral centre. All consecutive patients with NLUTD and a cumulative size of renal calculi greater than 15mm or 10mm in the lower calyx, who had extraction surgery between 2005 and 2020, were included. The primary endpoint was the one-session stone-free rate (SFR) at 3 months on a CT scan. The secondary endpoints were complication (Clavien-Dindo grading system), operative time, blood loss and length of hospital stay.

Results: We performed 76 standard PCNL (sPCNL), 46 flexible ureteroscopy lithotripsy (fURL) and 25 miniaturized PCNL (mPCNL). The one-session SFR was 37.5% for the mPCNL group, 38.2% for the sPCNL group and 37% for the fURL group with no significant difference between the three procedures (P=0.99). Early complications, blood loss and transfusion rates were lower in the mPCNL group than in the sPCNL group (P=0.047) and comparable to fURL group. The final SFRs after a second intervention for mPCNL, sPCNL and fURL were 48%, 61.8% and 63%, respectively (P=0.67).

Conclusion: The efficacy of mPCNL in patients with NLUTD was not different from other techniques, but a significantly lower rate of complications than sPCNL was observed.

Level of proof: 3.

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来源期刊
Progres En Urologie
Progres En Urologie 医学-泌尿学与肾脏学
CiteScore
1.80
自引率
27.30%
发文量
132
审稿时长
54 days
期刊介绍: Une publication rapide des travaux en urologie: retrouvez les derniers travaux de recherche, études et enquêtes, en Urologie, publiés sous la forme de revues, mises au point, articles originaux, notes techniques, cas cliniques pertinents et originaux, lettres à la rédaction, revues de la littérature, textes de recommandation,... La revue publie également des articles pour les infirmières en Urologie. Une approche pluridisciplinaire : Progrès en Urologie aborde toutes les pathologies urologiques. Aux 13 numéros de Progrès viennent s''ajouter 4 numéros de Progrès en Urologie Pelvi-Périnéologie
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