{"title":"嘌呤硫醇核苷抑制同型接枝反应。","authors":"A P KIMBALL, G A LEPAGE, B BOWMAN, S J HERRIOT","doi":"10.3181/00379727-119-30149","DOIUrl":null,"url":null,"abstract":"Summary Two purinethiol nucleosides, α-2′-deoxythioguanosine and arabinosyl-6-mercaptopurine, suppress the homograft response in mice without producing host toxicity. Graft survivals were increased at dosage levels that, in the latter case, produced little or no inhibition of the induction of humoral antibodies.","PeriodicalId":20675,"journal":{"name":"Proceedings of the Society for Experimental Biology and Medicine","volume":" ","pages":"248-52"},"PeriodicalIF":0.0000,"publicationDate":"1965-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3181/00379727-119-30149","citationCount":"6","resultStr":"{\"title\":\"SUPPRESSION OF THE HOMOGRAFT RESPONSE BY PURINETHIOL NUCLEOSIDES.\",\"authors\":\"A P KIMBALL, G A LEPAGE, B BOWMAN, S J HERRIOT\",\"doi\":\"10.3181/00379727-119-30149\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary Two purinethiol nucleosides, α-2′-deoxythioguanosine and arabinosyl-6-mercaptopurine, suppress the homograft response in mice without producing host toxicity. Graft survivals were increased at dosage levels that, in the latter case, produced little or no inhibition of the induction of humoral antibodies.\",\"PeriodicalId\":20675,\"journal\":{\"name\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"volume\":\" \",\"pages\":\"248-52\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1965-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.3181/00379727-119-30149\",\"citationCount\":\"6\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of the Society for Experimental Biology and Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3181/00379727-119-30149\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the Society for Experimental Biology and Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3181/00379727-119-30149","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
SUPPRESSION OF THE HOMOGRAFT RESPONSE BY PURINETHIOL NUCLEOSIDES.
Summary Two purinethiol nucleosides, α-2′-deoxythioguanosine and arabinosyl-6-mercaptopurine, suppress the homograft response in mice without producing host toxicity. Graft survivals were increased at dosage levels that, in the latter case, produced little or no inhibition of the induction of humoral antibodies.
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