玻璃体视网膜淋巴瘤患者表面光学相干断层血管造影显示血管周围花苞样病变。

Wenwen Chen, Junxiang Gu, Shixue Liu, Zhenyang Zhao, Tingting Jiang, Gezhi Xu, Qing Chang
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引用次数: 1

摘要

目的:描述玻璃体视网膜淋巴瘤在表面光学相干断层扫描(OCT)血管造影上的新特征——血管周围花苞样病变。方法:对2018年1月至2021年3月期间连续23例(35只眼)活检证实的玻璃体视网膜淋巴瘤患者进行回顾性图表回顾。对干预前后的ct血管造影图像进行分析。pfbl最初是在视网膜正中板的表面OCT血管造影上发现的,并通过其他成像方式进一步表征。结果:8例患者12眼(34.3%)检出血管周围花苞样病变,其中8眼最佳矫正视力在20/40及以上。12只眼中有10只在症状出现后6个月内检测到PFBLs。在表面OCT血管造影中,pfbl表现为围绕视网膜血管的点状点或汇合带,并累及动脉和静脉。12只眼中有4只眼以动脉为主。在OCT b扫描上,PFBLs通常表现为视网膜内高反射全层病变,与视网膜下色素上皮沉积(3眼,25%)和视网膜色素上皮不规则(4眼,33.3%)共定位。然而,PFBLs并不总是可以通过其他成像方式如眼底照片和眼底荧光素血管造影来识别。在所有随访的眼睛中,PFBLs在接受化疗或诊断性玻璃体切除术几个月后减弱或消退。结论:PFBLs是玻璃体视网膜淋巴瘤的特征性影像学表现,可能有助于玻璃体视网膜淋巴瘤的早期诊断,从而使治疗更加及时有效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PERIVASCULAR FLOWER-BUD-LIKE LESIONS ON EN FACE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN PATIENTS WITH VITREORETINAL LYMPHOMA.

Purpose: To describe perivascular flower-bud-like lesions (PFBLs) as novel characteristics of vitreoretinal lymphoma on en face optical coherence tomography (OCT) angiography.

Methods: A retrospective chart review was performed on 23 consecutive patients (35 eyes), who had biopsy-proven vitreoretinal lymphoma between January 2018 and March 2021. En face OCT angiography images were analyzed before and after intervention. PFBLs were initially identified on midretinal slabs of en face OCT angiography, and were further characterized by other imaging modalities.

Results: Perivascular flower-bud-like lesions were detected in 12 eyes (34.3%) of 8 patients, of which 8 eyes had best-corrected visual acuity of 20/40 or better. In 10 of the 12 eyes, PFBLs were detected within 6 months of symptom onset. On en face OCT angiography, PFBLs presented as punctate points or confluent bands surrounding retinal vessels, with arterial and venous involvement. In 4 of the 12 eyes, arteries were mainly affected. On OCT B-scans, PFBLs commonly appeared as hyperreflective full-thickness intraretinal lesions that colocalized with subretinal pigment epithelium deposits (3 eyes, 25%) and retinal pigment epithelium irregularities (4 eyes, 33.3%). However, PFBLs could not always be identified on other imaging modalities such as fundus photographs and fundus fluorescein angiography. In all eyes with follow-up, PFBLs attenuated or resolved months after receiving chemotherapy or diagnostic vitrectomy.

Conclusion: PFBLs are characteristic imaging findings of vitreoretinal lymphoma and may facilitate an early diagnosis of vitreoretinal lymphoma, which would in turn lead to more timely and effective treatment.

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