DNA损伤和双链断裂概述。

Q3 Biochemistry, Genetics and Molecular Biology

Enzymes Pub Date : 2022-01-01 Epub Date: 2022-10-07 DOI:10.1016/bs.enz.2022.08.001

Fuyuhiko Tamanoi, Kenichi Yoshikawa

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引用次数: 0

摘要

DNA受到了各种各样的攻击。因此，不同的损伤会累积在DNA上。这些变化包括碱基变化、单链断裂和双链断裂。在本卷中以及在接下来的卷中，我们将简要讨论DNA损伤和双链断裂。我们特别关注双链断裂。我们讨论了双链断裂的类型以及检测它们的方法。我们还讨论了DNA断裂是如何形成的。

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Overview of DNA damage and double-strand breaks.

DNA is under a variety of assaults. As a result, different damages accumulate on DNA. These include base changes, single-strand breaks and double-strand breaks. In this volume and also briefly in the following volume, we discuss DNA damage and double-strand breaks. In particular, we focus on double-strand breaks. We discuss types of double-strand breaks as well as methods to detect them. We also discuss how DNA breaks are formed.

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来源期刊

Enzymes Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

4.30

自引率

0.00%

发文量