B F Akinkunmi, O O Ogunkunle, F O Akinbami, A E Orimadegun
{"title":"伊巴丹大学学院医院重症恶性疟原虫疟疾患儿的心电图特征。","authors":"B F Akinkunmi, O O Ogunkunle, F O Akinbami, A E Orimadegun","doi":"10.4314/rejhs.v10i3.4","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The high burden of Malaria morbidity and mortality in children is due to its potential to cause multi-organ dysfunction. There is however limited information on the specific electrocardiographic features in falciparum malaria in paediatric age group.</p><p><strong>Aim: </strong>To investigate the electrocardiographic (ECG) features in children with (complicated) severe <i>falciparum</i> malaria (SM) and acute uncomplicated malaria (AUM) at the University College Hospital, Ibadan.</p><p><strong>Methods: </strong>This was a comparative cross-sectional study conducted among 398 children with symptomatic and confirmed Plasmodium falciparum malaria and apparently healthy controls. The frequencies of ECG features were described and compared among these children.</p><p><strong>Results: </strong>The prevalence of ECG abnormality was 79.7% and 63.2% in Severe Malaria SM and Acute uncomplicated malaria AUM patients, respectively. Sinus tachycardia was significantly more frequent in SM than AUM and control groups (p <0.001). The risk of an ECG abnormality was about three times higher in SM than healthy children (p<0.001; OR=2.89;95%CI[1.68,4.99).</p><p><strong>Conclusion: </strong>Severe malaria patients had significant ECG abnormalities (Sinus Tachycardia).</p>","PeriodicalId":29646,"journal":{"name":"Research Journal of Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/76/nihms-1841538.PMC9581379.pdf","citationCount":"0","resultStr":"{\"title\":\"Electrocardiographic features in children with severe falciparum malaria at the University College Hospital, Ibadan.\",\"authors\":\"B F Akinkunmi, O O Ogunkunle, F O Akinbami, A E Orimadegun\",\"doi\":\"10.4314/rejhs.v10i3.4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The high burden of Malaria morbidity and mortality in children is due to its potential to cause multi-organ dysfunction. There is however limited information on the specific electrocardiographic features in falciparum malaria in paediatric age group.</p><p><strong>Aim: </strong>To investigate the electrocardiographic (ECG) features in children with (complicated) severe <i>falciparum</i> malaria (SM) and acute uncomplicated malaria (AUM) at the University College Hospital, Ibadan.</p><p><strong>Methods: </strong>This was a comparative cross-sectional study conducted among 398 children with symptomatic and confirmed Plasmodium falciparum malaria and apparently healthy controls. The frequencies of ECG features were described and compared among these children.</p><p><strong>Results: </strong>The prevalence of ECG abnormality was 79.7% and 63.2% in Severe Malaria SM and Acute uncomplicated malaria AUM patients, respectively. Sinus tachycardia was significantly more frequent in SM than AUM and control groups (p <0.001). The risk of an ECG abnormality was about three times higher in SM than healthy children (p<0.001; OR=2.89;95%CI[1.68,4.99).</p><p><strong>Conclusion: </strong>Severe malaria patients had significant ECG abnormalities (Sinus Tachycardia).</p>\",\"PeriodicalId\":29646,\"journal\":{\"name\":\"Research Journal of Health Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/76/nihms-1841538.PMC9581379.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research Journal of Health Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4314/rejhs.v10i3.4\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/9/28 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Journal of Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/rejhs.v10i3.4","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/9/28 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Electrocardiographic features in children with severe falciparum malaria at the University College Hospital, Ibadan.
Introduction: The high burden of Malaria morbidity and mortality in children is due to its potential to cause multi-organ dysfunction. There is however limited information on the specific electrocardiographic features in falciparum malaria in paediatric age group.
Aim: To investigate the electrocardiographic (ECG) features in children with (complicated) severe falciparum malaria (SM) and acute uncomplicated malaria (AUM) at the University College Hospital, Ibadan.
Methods: This was a comparative cross-sectional study conducted among 398 children with symptomatic and confirmed Plasmodium falciparum malaria and apparently healthy controls. The frequencies of ECG features were described and compared among these children.
Results: The prevalence of ECG abnormality was 79.7% and 63.2% in Severe Malaria SM and Acute uncomplicated malaria AUM patients, respectively. Sinus tachycardia was significantly more frequent in SM than AUM and control groups (p <0.001). The risk of an ECG abnormality was about three times higher in SM than healthy children (p<0.001; OR=2.89;95%CI[1.68,4.99).
Conclusion: Severe malaria patients had significant ECG abnormalities (Sinus Tachycardia).
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