Anna M Parenteau, Nicholas V Alen, Jennifer La, Alison T Luck, Devin J Teichrow, Enya M Daang, Adam T Nissen, LillyBelle K Deer, Camelia E Hostinar
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引用次数: 1
摘要
与气候变化有关的灾害使人们更加关注空气污染对健康的影响。9 ~ 11岁儿童122例,M(SD) = 9.91(0.56)。参与者家附近的颗粒物(PM2.5)水平是从美国环境保护局(Environmental Protection Agency)获得的。从100个儿童血清样本中检测细胞因子:IL-6、IL-8、IL-10和tnf - α。自主生理学指标包括射血前期(PEP)、呼吸窦性心律失常(RSA)、心脏自主调节(CAR)和心脏自主平衡(CAB)。IL-6与每日PM2.5呈正相关(r = 0.26, p = 0.009)。IL-8与月度PM2.5呈负相关(r = -)。23, p = .02)。PEP与每日PM2.5 (r = 0.29, p = .001)和月度PM2.5 (r = 0.18, p = .044)呈正相关。CAR与每日PM2.5呈负相关(r = -)。29, p = .001)。IL-10、TNFα、RSA和CAB与PM2.5无相关性。空气污染可能会增加儿童患炎症的风险。
Associations of air pollution with peripheral inflammation and cardiac autonomic physiology in children.
Climate change-related disasters have drawn increased attention to the impact of air pollution on health. 122 children ages 9-11 years old, M(SD) = 9.91(.56), participated. Levels of particulate matter (PM2.5) near participants' homes were obtained from the Environmental Protection Agency. Cytokines were assayed from 100 child serum samples: IL-6, IL-8, IL-10, and TNFα. Autonomic physiology was indexed by pre-ejection period (PEP), respiratory sinus arrhythmia (RSA), cardiac autonomic regulation (CAR), and cardiac autonomic balance (CAB). IL-6 was positively related to daily PM2.5 (r = .26, p = .009). IL-8 was negatively associated with monthly PM2.5 (r = -.23, p = .02). PEP was positively related to daily (r = .29, p = .001) and monthly PM2.5 (r = .18, p = .044). CAR was negatively associated with daily PM2.5 (r = -.29, p = .001). IL-10, TNFα, RSA, and CAB were not associated with PM2.5. Air pollution may increase risk of inflammation in children.
期刊介绍:
The mission of New Directions for Child and Adolescent Development is to provide scientific and scholarly presentations on cutting edge issues and concepts in the field of child and adolescent development. Each issue focuses on a specific new direction or research topic, and is peer reviewed by experts on that topic. Any topic in the domain of child and adolescent development can be the focus of an issue. Topics can include social, cognitive, educational, emotional, biological, neuroscience, health, demographic, economical, and socio-cultural issues that bear on children and youth, as well as issues in research methodology and other domains. Topics that bridge across areas are encouraged, as well as those that are international in focus or deal with under-represented groups. The readership for the journal is primarily students, researchers, scholars, and social servants from fields such as psychology, sociology, education, social work, anthropology, neuroscience, and health. We welcome scholars with diverse methodological and epistemological orientations.