系统评价:影像学检查对喉癌放疗后复发诊断的准确性。

Head & Neck Pub Date : 2008-07-01 DOI:10.1002/hed.20790
Jolijn Brouwer, Lotty Hooft, Otto S Hoekstra, Ingrid I Riphagen, Jonas A Castelijns, Remco de Bree, C René Leemans
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引用次数: 0

摘要

背景:放射治疗后喉复发肿瘤的诊断具有挑战性。最可靠的方法是全麻下直接喉镜检查。然而,许多无效的喉镜检查是在无疾病的患者中进行的。影像学检查对选择这种侵入性手术的患者是有用的。本系统综述的目的是总结现有证据并确定CT、MRI、铊-201 (201Tl)闪烁成像和f -18氟脱氧葡萄糖正电子发射断层扫描(18FDG-PET)的诊断准确性。方法:根据Cochrane协作网的指南进行系统评价。两位审稿人根据A-、B-和c项给文章打分。进行统计荟萃分析,得出敏感性和特异性的汇总估计。结果:18FDG-PET有8项符合条件的研究。18FDG-PET研究的有效性是合理的;敏感性和特异性的合并估计(95% CI)分别为89%和74%。结论:18FDG-PET的诊断准确性是有希望的,值得进行一项随机试验,比较基于传统诊断检查的策略和基于18FDG-PET的策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Systematic review: accuracy of imaging tests in the diagnosis of recurrent laryngeal carcinoma after radiotherapy.

Background: Diagnosing recurrent laryngeal tumor after radiotherapy is challenging. The most reliable method is direct laryngoscopy under general anesthesia. However, many futile laryngoscopies are performed in disease-free patients. Imaging tests selecting patients for this invasive procedure would be useful. The aim of this systematic review was summarizing the available evidence and determining the diagnostic accuracy of CT, MRI, thallium-201 (201Tl) scintigraphy, and F-18-fluorodeoxyglucose positron emission tomography (18FDG-PET).

Methods: A systematic review was performed according to the guidelines of the Cochrane Collaboration. Two reviewers scored the articles according to A-, B-, and C-items. Statistical meta-analysis was performed producing summary pooled estimates of sensitivity and specificity.

Results: There were 8 eligible studies on 18FDG-PET. The validity of the 18FDG-PET studies was reasonable; the pooled estimates (95% CI) for sensitivity and specificity were 89% and 74%.

Conclusion: The diagnostic accuracy of 18FDG-PET is promising and warrants a randomized trial comparing a strategy based on conventional diagnostic work-up to one based on 18FDG-PET.

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